Clinical Report: Primary Extranodal Marginal Zone B-cell Lymphoma in the Right Lateral Ventricle
Overview
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Background
Primary CNS MALT lymphoma is a rare, low-grade B-cell lymphoma that typically arises in the dura, with intraventricular occurrences being exceedingly rare. Accurate diagnosis is critical as these tumors can be misidentified as meningiomas or metastases on imaging. Understanding the clinical features and treatment options for this lymphoma subtype is essential for improving patient outcomes.
Data Highlights
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Key Findings
Only eight cases of ventricular MALT lymphoma have been previously reported.
Chronic inflammation may be implicated in MALT lymphomas, but specific triggers for ventricular cases remain unclear.
Intraventricular MALT lymphoma is often misdiagnosed as meningioma or metastasis.
Histopathological confirmation is crucial for accurate diagnosis and differentiation from DLBCL.
Maximal safe resection followed by involved-site radiotherapy is the recommended management approach.
Clinical Implications
Clinicians should consider MALT lymphoma in the differential diagnosis of intraventricular lesions, especially when imaging suggests meningioma or metastasis. Accurate histopathological evaluation is essential for proper diagnosis and treatment planning.
Conclusion
This case underscores the importance of recognizing primary CNS MALT lymphoma as a potential diagnosis in patients with ventricular lesions, emphasizing the need for careful diagnostic evaluation and tailored treatment strategies.
