Brain-based symptoms reported in young adults evaluated for cervical spine etiology: a retrospective, cross-sectional clinical study with preliminary data on over 200 patients - Report - MDSpire

Brain-based symptoms reported in young adults evaluated for cervical spine etiology: a retrospective, cross-sectional clinical study with preliminary data on over 200 patients

  • By

  • Ross A. Hauser

  • Morgan Griffiths

  • Ashley Watterson

  • Danielle Matias

  • Cam Steilen

  • Benjamin Ryan Rawlings

  • May 25, 2026

  • 0 min

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Evaluation of Cervical Spine Abnormalities in Young Adults with Brain-Related Symptoms

Overview

This study investigates cervical spine abnormalities in young adults presenting with brain-based symptoms. Findings indicate a high prevalence of structural cervical dysfunction, which may contribute to these symptoms.

Background

Brain-based symptoms, which include cognitive and psychological issues, are increasingly reported among young adults. Understanding the potential underlying cervical spine abnormalities could provide insights into the etiology of these symptoms and inform treatment strategies. This study aims to explore these associations in a clinical population.

Data Highlights

FindingPercentage
Forward head posture100%
Decreased cervical lordotic curve90%
C1–C2 ligamentous cervical instability87%
Decreased vagus nerve CSA95%
Decreased IJV CSA98%
Elevated ONSD99%

Key Findings

  • 100% of patients exhibited forward head posture.
  • 90% had a decreased depth of cervical lordotic curve.
  • 87% presented with C1–C2 ligamentous cervical instability.
  • 95% showed significantly decreased vagus nerve cross-sectional area.
  • 98% had decreased internal jugular vein cross-sectional area.
  • 99% exhibited elevated optic nerve sheath diameters.

Clinical Implications

The findings suggest that cervical spine abnormalities may play a role in the presentation of brain-based symptoms. Clinicians should consider evaluating cervical spine structure in young adults with unexplained neurological symptoms.

Conclusion

This study highlights the significant prevalence of cervical spine abnormalities in young adults with brain-based symptoms, warranting further investigation into their potential role in symptomatology.

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