Clinical Report: Investigating the Impact of Therapeutic Horticulture on NSSI

Overview

This report outlines a randomized controlled trial aimed at evaluating the effects of Therapeutic Horticulture (TH) on non-suicidal self-injury (NSSI) and psychosocial functioning in adolescents diagnosed with major depressive disorder (MDD). The study seeks to address the urgent need for effective interventions in this population.

Background

The rising incidence of major depressive disorder (MDD) and non-suicidal self-injury (NSSI) among adolescents poses a significant public health challenge. Traditional interventions often face limitations, highlighting the need for innovative treatment options. Therapeutic Horticulture (TH) presents a novel approach that may engage adolescents in meaningful therapeutic activities, potentially improving their mental health outcomes.

Data Highlights

This study will involve 66 participants, randomized into intervention and control groups, with outcomes assessed at baseline and post-intervention.

Key Findings

• Therapeutic Horticulture (TH) engages adolescents in gardening activities to achieve therapeutic effects.
• The trial will assess the severity of NSSI as the primary outcome, alongside secondary outcomes including depression and sleep quality.
• Participants must meet specific inclusion criteria, including a diagnosis of MDD and NSSI per DSM-5.
• The control group will receive treatment as usual, while the intervention group will receive TH for two weeks.
• This study may provide evidence for future clinical interventions targeting adolescents with comorbid MDD and NSSI.

Clinical Implications

The findings from this trial could inform clinical practice by introducing TH as a potential adjunctive treatment for adolescents with MDD and NSSI. Clinicians may consider incorporating horticultural therapy into treatment plans to enhance engagement and therapeutic outcomes.

Conclusion

This trial aims to explore the efficacy of Therapeutic Horticulture in addressing NSSI among adolescents with MDD, potentially offering a novel intervention for this vulnerable population.

Related Resources & Content

1. Frontiers in Psychiatry, 2026 -- The association of different dimensions of anhedonia in the relationship between depressive symptoms and self-harm in adolescents with mood disorders
2. Frontiers in Psychiatry, 2026 -- Predictive value of antioxidant and thyroid function indicators for non-suicidal self-injury in adolescents with major depressive disorder
3. JAMA Network Open, 2026 -- Dual-Site aiTBS for Suicidal Ideation in Adolescents With Major Depressive Disorder: A Randomized Clinical
4. NICE, 2024 -- Recommendations | Self-harm: assessment, management and preventing recurrence
5. BMC Psychiatry (Springer) — School-based group interpersonal therapy for adolescents with depression in Nepal: protocol for a phase III realist cluster-randomised controlled trial
6. Recommendations | Self-harm: assessment, management and preventing recurrence | Guidance | NICE
7. The Effectiveness of Emotion Regulation–Focused Interventions on Non-Suicidal Self-injury: A Meta-Analysis | Cognitive Therapy and Research | Springer Nature Link
8. Nurse‑led horticultural activities as an early intervention for mild‑to‑moderate depressive symptoms among youth in Hong Kong: an exploratory randomised controlled trial | BMC Public Health | Springer Nature Link