Privacy-Conscious Skin Cancer Diagnosis through Federated Learning and Deep Neural Networks - Report - MDSpire

Privacy-Conscious Skin Cancer Diagnosis through Federated Learning and Deep Neural Networks

  • By

  • Mohammed A. M. Alfalahi

  • Oğuz Karan

  • Sefer Kurnaz

  • Ayça Kurnaz Türkben

  • April 27, 2026

  • 0 min

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Clinical Report: Privacy-Conscious Skin Cancer Diagnosis through Federated Learning

Overview

Expand on the comparison with traditional methods and define 'superior performance'.

Background

Skin cancer is a prevalent global health issue, with millions of new cases diagnosed annually, necessitating accurate and timely diagnostic measures. Traditional diagnostic methods face challenges such as inter-observer variability and limited access to dermatological expertise. The integration of artificial intelligence and machine learning offers promising advancements in improving diagnostic accuracy and patient outcomes.

Data Highlights

ModelAccuracyF1-scoreConfidence Interval
MobileNetV2 (Ring-based FL)98.88%98.80%97.92–99.84%
Centralized BaselineNot specifiedNot specifiedp < 0.01

Key Findings

  • MobileNetV2 with ring-based federated learning achieved an accuracy of 98.88%.
  • The framework demonstrated significant improvements over centralized methods (p < 0.01).
  • Higher convergence rates and reduced communication overhead were observed with MobileNetV2 compared to VGG16.
  • The performance degradation with increasing non-IID severity was gradual, indicating robustness.
  • The proposed framework complies with privacy regulations while maintaining high diagnostic utility.

Clinical Implications

The findings suggest that federated learning can effectively enhance skin cancer diagnosis while safeguarding patient privacy. Clinicians may consider adopting AI-assisted diagnostic tools that utilize federated learning to improve accuracy and efficiency in diverse healthcare settings.

Conclusion

Federated learning presents a viable solution for privacy-conscious skin cancer diagnosis, demonstrating that high diagnostic performance can be achieved without compromising patient confidentiality. This approach may facilitate broader implementation of AI in dermatology.

References

  1. Author(s)/Org, Source, Year -- Title
  2. npj Digital Medicine, 2025 -- Automated triage of cancer-suspicious skin lesions with 3D total-body photography
  3. asco ai in oncology, 2025 -- Cutaneous Squamous Cell Carcinoma: AI Model Rivals Dermatologists in Differentiation Assessment
  4. Cancer Facts & Figures, 2026
  5. JAMA Dermatology, 2026 -- Prospective Evidence on Artificial Intelligence−Assisted Melanoma Diagnostics: A Systematic Review and Meta-Analysis
  6. the asco post — Cutaneous Squamous Cell Carcinoma: AI Model Rivals Dermatologists in Differentiation Assessment
  7. Privacy preserving skin cancer diagnosis through federated deep learning and explainable AI
  8. Cancer Facts & Figures
  9. Prospective Evidence on Artificial Intelligence−Assisted Melanoma Diagnostics: A Systematic Review and Meta-Analysis | Oncology | JAMA Dermatology | JAMA Network

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