Adjunctive Psychosocial Interventions and Opioid Abstinence Among Patients Receiving Buprenorphine: A - Report - MDSpire

Adjunctive Psychosocial Interventions and Opioid Abstinence Among Patients Receiving Buprenorphine: A

  • By

  • Michelle R. Lent

  • Emily E. Hurstak

  • Kevin G. Lynch

  • Emily Loscalzo

  • Kimberly Mazur

  • Helen L. Lugo

  • Karen L. Dugosh

  • June 23, 2026

  • 0 min

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Clinical Report: The Impact of Complementary Psychosocial Support on Opioid Abstinence

Overview

This study evaluates the effects of cognitive-behavioral therapy (CBT) and peer recovery support (PRS) on opioid use and treatment retention among patients receiving buprenorphine for opioid use disorder (OUD).

Background

Opioid use disorder (OUD) is a significant public health issue, contributing to high rates of overdose and mortality. Effective interventions that address the complex medical, psychiatric, and psychosocial factors associated with OUD are essential for improving recovery outcomes. Despite the availability of medications for opioid use disorder (MOUD), such as buprenorphine, their utilization and retention rates remain suboptimal.

Data Highlights

ConditionParticipants
MOUD treatment as usual85
MOUD with CBT85
MOUD with PRS85
MOUD with CBT and PRS85

Key Findings

  • The study involved 340 adults with OUD receiving office-based buprenorphine treatment.
  • Participants were randomly assigned to one of four treatment conditions: TAU, MOUD with CBT, MOUD with PRS, and MOUD with both CBT and PRS.
  • Follow-up assessments were conducted at 3, 6, 9, and 12 months post-enrollment.
  • Severe adverse events were monitored, with 51 events reported, none deemed study-related.
  • Participants received financial incentives for participation and follow-up assessments.

Clinical Implications

The study highlights the importance of integrating psychosocial support into treatment plans for patients with OUD. Understanding the effectiveness of these interventions can guide healthcare professionals in optimizing treatment strategies for improved patient outcomes.

Conclusion

The study reports on the effects of complementary psychosocial support on treatment retention and opioid use among individuals receiving buprenorphine for OUD.

Related Resources & Content

  1. JAMA Internal Medicine, 2023 -- Extended-Release vs Sublingual Buprenorphine in Pregnancy Through 12 Months Post Partum: A Randomized Clinical
  2. JAMA Network Open, 2023 -- Policy and Payment Factors Influencing Adoption of Low-Barrier Buprenorphine Treatment
  3. JAMA Network Open, 2023 -- High-Deductible Health Plan Enrollment and Buprenorphine Dispensing
  4. Journal of Addiction Medicine -- The ASAM National Practice Guideline for the Treatment of Opioid Use Disorder
  5. Comparison of Behavioral Treatment Conditions in Buprenorphine Maintenance - PMC
  6. Contingency Management for Patients Receiving Medication for Opioid Use Disorder: A Systematic Review and Meta-analysis - PMC
  7. JAMA Internal Medicine — Error in Conclusions
  8. Journal of Addiction Medicine
  9. Comparison of Behavioral Treatment Conditions in Buprenorphine Maintenance - PMC
  10. Contingency Management for Patients Receiving Medication for Opioid Use Disorder: A Systematic Review and Meta-analysis - PMC

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