Deep Neuromuscular Blockade in Laparoscopic One-Anastomosis Gastric Bypass (OAGB): A Randomized Controlled Trial - Report - MDSpire

Deep Neuromuscular Blockade in Laparoscopic One-Anastomosis Gastric Bypass (OAGB): A Randomized Controlled Trial

  • By

  • Nikolas Drakos

  • Stella Antoniou

  • Ioannis D. Kostakis

  • Diamanto Aretha

  • Sofia Bregianni

  • Christina Kalogeropoulou

  • George Skroubis

  • June 16, 2026

  • 0 min

Share

Evaluation of Deep Neuromuscular Blockade During Laparoscopic OAGB Surgery

Overview

This randomized controlled study evaluates the effects of deep versus moderate neuromuscular blockade (NMB) during laparoscopic one-anastomosis gastric bypass (OAGB).

Background

Bariatric surgery is crucial for achieving significant weight loss and improving obesity-related comorbidities. The laparoscopic approach is integral to enhanced recovery after surgery (ERAS) protocols, yet challenges such as abdominal muscle contractions can hinder surgical visibility.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • Deep NMB was associated with improved surgical workspace quality compared to moderate NMB.
  • Intraoperative evaluation utilized the five-point Leiden Surgical Rating Scale (LSRS).
  • Deep NMB was associated with better lung mechanics during surgery.
  • Postoperative complications, including atelectasis, were assessed using objective imaging methods.
  • All procedures were performed by a single experienced surgeon to maintain consistency.

Clinical Implications

The study presents findings on deep NMB in laparoscopic bariatric procedures, focusing on surgical conditions and respiratory complications.

Conclusion

Further investigation is warranted regarding the role of deep neuromuscular blockade during laparoscopic OAGB surgery.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Author(s)/Org, Source, Year -- Title
  3. Author(s)/Org, Source, Year -- Title
  4. Guidelines for Perioperative Care in Bariatric Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations: A 2021 Update - PMC
  5. Anesthesiology -- American Society of Anesthesiologists Practice Guidelines, 2023
  6. Obesity Surgery — The Effect of Erector Spinae Plane Block on Diaphragmatic Function After Laparoscopic Sleeve Gastrectomy in Patients with Morbid Obesity: A Double-Blind Randomized Controlled Study
  7. IFSO Position Statement on One-Anastomosis Gastric Bypass
  8. Guidelines for Perioperative Care in Bariatric Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations: A 2021 Update - PMC
  9. Anesthesiology
  10. Reprinted from EUROPEAN JOURNAL OF ANAESTHESIOLOGY
  11. Deep Neuromuscular Block Improves Surgical Conditions during Bariatric Surgery and Reduces Postoperative Pain: A Randomized Double Blind Controlled Trial | PLOS One
  12. Deep Neuromuscular Blockade Improves Laparoscopic Surgical Conditions: A Randomized, Controlled Study - PubMed
  13. Does deep neuromuscular blockade during laparoscopy procedures change patient, surgical, and healthcare resource outcomes? A systematic review and meta-analysis of randomized controlled trials - PMC
  14. Quality of recovery after laparoscopic cholecystectomy: a randomized trial of pneumoperitoneum pressure and neuromuscular blockade depth - PubMed
  15. The Role of Deep Neuromuscular Blockade and Sugammadex in Laparoscopic Hysterectomy: A Randomized Controlled Trial

Original Source(s)

Related Content