The Rise of Indigenous Dengue Fever Cases in Iran: An In-Depth Examination of the Initial Significant Outbreak in Sistan and Baluchestan Province, 2024 - Report - MDSpire

The Rise of Indigenous Dengue Fever Cases in Iran: An In-Depth Examination of the Initial Significant Outbreak in Sistan and Baluchestan Province, 2024

  • By

  • Madineh Abbasi

  • Ehsan Sheykh Noori

  • Faramarz Mobaraki

  • Omid Dehghan

  • Fatemeh Nikpour

  • Ahmad Raeisi

  • Abdolreza Mirolyaie

  • Mahasti Alizadeh

  • Ahmad Koosha

  • Saideh Yousefi

  • February 6, 2026

  • 0 min

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Clinical Report: The Rise of Indigenous Dengue Fever Cases in Iran, 2024

Overview

This report examines the significant outbreak of dengue fever in Sistan and Baluchestan Province, Iran, in 2024, highlighting the establishment of Aedes aegypti as a key factor in local transmission. The findings underscore the urgent need for enhanced surveillance and vector control measures in the region.

Background

Dengue fever is a major arboviral disease with increasing global incidence, particularly in tropical and subtropical regions. The emergence of local transmission in Iran, particularly in Sistan and Baluchestan Province, poses a significant public health challenge due to the presence of competent mosquito vectors and the country's connectivity with endemic regions. Understanding the dynamics of this outbreak is crucial for effective management and prevention strategies.

Data Highlights

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Key Findings

  • The first detection of Aedes aegypti in Chabahar, Sistan and Baluchestan Province, occurred in late 2023, enabling local dengue transmission in 2024.
  • Approximately 80% of dengue infections are asymptomatic, complicating diagnosis and management.
  • There is currently no universally approved treatment or vaccine for dengue fever, making prevention through mosquito control essential.
  • Socio-economic conditions, urbanization, and climate change contribute to the rising incidence of dengue fever globally.
  • WHO classifies the dengue risk in Iran as high due to established Aedes populations and frequent travel from endemic countries.

Clinical Implications

Healthcare professionals must prioritize awareness and training regarding dengue fever to improve timely diagnosis and management. Enhanced vector control measures and public health education are critical to mitigate the risk of outbreaks in vulnerable regions like Sistan and Baluchestan.

Conclusion

The emergence of indigenous dengue cases in Iran highlights the need for immediate public health interventions and ongoing surveillance to prevent further outbreaks. Addressing the factors contributing to dengue transmission is essential for safeguarding public health in the region.

References

  1. WHO, Disease Outbreak News, 2024 -- Dengue – Iran (Islamic Republic of)
  2. WHO, Guidelines for Clinical Management of Arboviral Diseases, 2025 -- WHO guidelines for clinical management of arboviral diseases: dengue, chikungunya, Zika and yellow fever
  3. WHO, Position Paper, 2024 -- WHO position paper on dengue vaccines, May 2024
  4. Infection — Emergence of Localized Dengue Cases in Fano, Pesaro-Urbino Province - Marche Region, Italy, September 2024
  5. The Journal of Infectious Diseases — Identification of Two Novel Lineages of Dengue Virus Serotype 2 in Yunnan, China, 2024
  6. Open Forum Infectious Diseases — Epidemiological Insights into Dengue and COVID-19 Co-infection in Dhaka, Bangladesh (2021–2023): Findings from a Cross-sectional Analysis
  7. The Journal of Infectious Diseases — Simultaneous Cocirculation of 2 Genotypes of Dengue Virus Serotype 3 Causing a Large Outbreak in Sri Lanka in 2023
  8. Dengue – Iran (Islamic Republic of)
  9. WHO guidelines for clinical management of arboviral diseases: dengue, chikungunya, Zika and yellow fever
  10. WHO position paper on dengue vaccines, May 2024

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