Latest developments in the use of e-cigarettes by people with schizophrenia spectrum disorders who smoke: a scoping review - Report - MDSpire

Recent Insights into E-Cigarette Utilization Among Smokers with Schizophrenia Spectrum Disorders: A Scoping Review

  • By

  • Pasquale Caponnetto

  • Sarah Pratt

  • Carlo Maria Bellanca

  • Noemi Maria Vitale

  • Graziella Chiara Prezzavento

  • Giusy Rita Maria La Rosa

  • Yusuff Adebayo Adebisi

  • Ramin Nilforooshan

  • Isaac John

  • Abdulnaser Fakhrou

  • Antonino Petralia

  • Maria Salvina Signorelli

  • Uladzimir Pikirenia

  • Ines Testoni

  • Roberto Cavallaro

  • Marta Bosia

  • Riccardo Polosa

  • July 21, 2026

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Clinical Report: Recent Insights into E-Cigarette Utilization Among Smokers with SSD

Overview

This scoping review evaluates the use of e-cigarettes among individuals with schizophrenia spectrum disorders (SSD).

Background

Tobacco use is disproportionately high among individuals with schizophrenia spectrum disorders, leading to increased mortality from smoking-related diseases. Traditional cessation methods are less effective in this population, necessitating exploration of alternative approaches such as e-cigarettes.

Data Highlights

Three studies with a total of 323 participants were included in the review.

Key Findings

  • E-cigarette interventions are feasible and acceptable for individuals with SSD.
  • Preliminary evidence suggests e-cigarettes may lead to smoking reduction.
  • Decreased exposure to tobacco-related carcinogens was observed.

Clinical Implications

Healthcare providers should consider the unique challenges faced by individuals with SSD when discussing smoking cessation options. E-cigarettes may offer a viable alternative, but their use should be accompanied by behavioral support to enhance effectiveness.

Conclusion

Further research is necessary to confirm these results.

Related Resources & Content

  1. Pratt et al., Frontiers in Psychiatry, 2026 -- Recent Insights into E-Cigarette Utilization Among Smokers with SSD
  2. The ASCO Post — Electronic Cigarette Use and Smoking Among Adolescents
  3. Archives of Toxicology — Growing Awareness of Toxicological Issues Related to E-Cigarettes and Vaping
  4. DIGITAL HEALTH — Utility and usability testing of the FrESH (free from E-Cigarettes and smoking for health) web application: A qualitative study
  5. American Journal of Epidemiology — Link Between Natural E-Cigarette Use and Smoking Cessation Among Adults in the United States
  6. VA/DOD Clinical Practice Guideline for Tobacco Use Treatment
  7. NICE Guideline NG209 on Treating Tobacco Dependence
  8. Recommendation: Tobacco Smoking Cessation in Adults, Including Pregnant Persons: Interventions | United States Preventive Services Taskforce
  9. 2024 exceptional surveillance of tobacco: preventing uptake, promoting quitting and treating dependence (NICE guideline NG209) - NCBI Bookshelf
  10. The health effects of vaping and e-cigarettes: consensus recommendations
  11. Electronic Nicotine-Delivery Systems for Smoking Cessation | New England Journal of Medicine
  12. Electronic Cigarettes vs Varenicline for Smoking Cessation in Adults: A Randomized Clinical Trial - PubMed
  13. The Effect of 12-Week e-Cigarette Use on Smoking Abstinence at 1 Year: The E3 Trial - PMC
  14. Effect of unguided e-cigarette provision on uptake, use, and smoking cessation among adults who smoke in the USA: a naturalistic, randomised, controlled clinical trial - ScienceDirect
  15. Frontiers | Latest developments in the use of e-cigarettes by people with schizophrenia spectrum disorders who smoke: a scoping review
  16. Changes in combustible cigarette and electronic nicotine delivery system use among people with and without schizophrenia spectrum disorders in the USA (2016–2023) - PMC

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