Prevalence and clinical determinants of diabetic gastroparesis in type 2 diabetes: a symptom- and scintigraphy-based cross-sectional study - Report - MDSpire

Prevalence and clinical determinants of diabetic gastroparesis in type 2 diabetes: a symptom- and scintigraphy-based cross-sectional study

  • By

  • Marwa M Abokresha

  • Mena Adley Wahba Tousb

  • Manal Esayed Ez Elden

  • Waleed Ahmed Diab

  • Bahaa O Taha

  • June 16, 2026

  • 0 min

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Clinical Report: Frequency and Clinical Factors Associated with Diabetic Gastroparesis

Overview

This study investigates the prevalence and clinical factors associated with diabetic gastroparesis (DG) in individuals with type 2 diabetes (T2D). It highlights the importance of symptom-based screening tools and objective gastric emptying measurements in diagnosing DG.

Background

Diabetic gastroparesis is a significant complication of diabetes mellitus, affecting patient quality of life due to gastrointestinal symptoms such as nausea and early satiety. The condition is often underdiagnosed, particularly in T2D, where symptoms may be misattributed to other gastrointestinal disorders. Understanding the clinical factors associated with DG is crucial for improving diagnosis and management in this growing patient population.

Data Highlights

No numerical data or trial results were provided in the source material.

Key Findings

  • Diabetic gastroparesis is more prevalent in type 1 diabetes than in type 2 diabetes.
  • Symptoms of gastroparesis include early satiety, nausea, vomiting, and abdominal fullness.
  • Uncontrolled blood glucose is a primary risk factor for developing diabetic gastroparesis.
  • Female gender, longer diabetes duration, and diabetic microvascular complications are associated with higher risk of DG.
  • The Gastroparesis Cardinal Symptom Index (GCSI) is a validated tool for assessing symptom severity but requires further evaluation for diagnostic accuracy.

Clinical Implications

Healthcare professionals should be vigilant in recognizing symptoms of diabetic gastroparesis in patients with type 2 diabetes to ensure timely diagnosis and management. Utilizing both symptom-based assessments and objective testing can enhance diagnostic accuracy and improve patient outcomes.

Conclusion

Diabetic gastroparesis is a prevalent yet often overlooked complication in type 2 diabetes. Enhanced awareness and diagnostic strategies are essential for effective management of this condition.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- Gender differences in symptoms suggestive of diabetic gastroparesis in the West Bank: clinical insights from a cross-sectional study
  2. The New Gastroenterologist, 2025 -- Updated Guidelines on Gastroparesis Released by AGA
  3. Journal of Gastrointestinal Surgery, 2022 -- Evaluating Pyloric Function in Gastroparesis Patients Compared to Individuals Post-Esophagectomy Using Endoluminal Functional Lumen Imaging Probe (EndoFLIP™)
  4. AGA Clinical Practice Guideline on Management of Gastroparesis - ScienceDirect
  5. Obesity Surgery — Exploratory Clinical Study on Gastrointestinal Transit Using Dual-Isotope Scintigraphy in Patients Undergoing Duodenal Switch Surgery
  6. Clinical insights into diabetic gastroparesis: gastric scintigraphy-based diagnosis and treatment outcomes | BMC Gastroenterology | Full Text
  7. AGA Clinical Practice Guideline on Management of Gastroparesis - ScienceDirect

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