Hyperuricemia in hospitalized patients with heart failure: prevalence and clinical correlates - Report - MDSpire

Hyperuricemia in hospitalized patients with heart failure: prevalence and clinical correlates

  • By

  • Lingqin Li

  • Xinzhu Yuan

  • Yanni Zhang

  • Quanbo Zhang

  • Yufeng Qing

  • July 15, 2026

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Prevalence and Clinical Associations of Hyperuricemia in Patients with Heart Failure During Hospitalization

Overview

This study evaluated the prevalence of hyperuricemia in hospitalized heart failure patients in China, finding a prevalence of 69.42%. Hyperuricemia was independently associated with renal dysfunction, hemodynamic impairment, electrolyte imbalance, and metabolic disturbance.

Background

Hyperuricemia is commonly observed in patients with heart failure and is linked to various chronic conditions.

Data Highlights

No numerical data available for tabulation.

Key Findings

  • The overall prevalence of hyperuricemia in hospitalized heart failure patients was 69.42%.
  • Prevalence of hyperuricemia was consistent across sex, age, and BMI groups.
  • Hyperuricemia was independently associated with renal dysfunction markers.
  • Nonlinear associations were observed for potassium, BNP, eGFR, and HDL-C.
  • Hyperuricemia varied by NYHA class among heart failure patients.

Clinical Implications

Clinicians should be aware of the high prevalence of hyperuricemia in heart failure patients and its association with renal and metabolic disturbances.

Conclusion

Hyperuricemia is prevalent among hospitalized heart failure patients and is associated with significant clinical correlates.

Related Resources & Content

  1. Zhang et al., Clinical Report, 2023 -- Prevalence and Clinical Associations of Hyperuricemia in Patients with Heart Failure During Hospitalization
  2. Clinical Rheumatology — Hyperuricemia in Psoriatic Arthritis: Increased Peripheral Involvement, Destructive Progression, and Treatment Challenges
  3. Clinical Research in Cardiology — Examining the Link Between Gout and Future Cardiovascular Events: A Retrospective Cohort Analysis of 132,000 Primary Care Outpatients in Germany Utilizing Propensity Score Matching
  4. Frontiers in Endocrinology — Serum uric acid levels and cardiorenal complication prevalence in hypertensive patients before and after the COVID-19 pandemic: a retrospective cross-sectional study from a tertiary traditional Chinese medicine hospital
  5. ESC GUIDELINES
  6. Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The EXACT-HF Study
  7. Serum uric acid fluctuations and cardiovascular outcomes in hospitalized acute heart failure patients - ScienceDirect

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