Cognitive reappraisal mediated the relationship between childhood emotional neglect and suicidality in depressed adolescents and young adults with NSSI behavior - Report - MDSpire

Cognitive reappraisal mediated the relationship between childhood emotional neglect and suicidality in depressed adolescents and young adults with NSSI behavior

  • By

  • Keliang Pan

  • Tingyu Hu

  • Guojian Yan

  • Guocheng Zhao

  • Yu Wang

  • Wanhong Peng

  • Zheyu Liu

  • Shiya Zhang

  • Lan Hu

  • May 13, 2026

  • 0 min

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Clinical Report: The Role of Cognitive Reappraisal in Linking Childhood Emotional Neglect to Suicidal Thoughts

Overview

This study investigates the relationship between childhood emotional neglect and suicidal ideation in depressed youth with non-suicidal self-injury (NSSI), highlighting cognitive reappraisal as a mediating factor. Emotional neglect was found to be a significant predictor of increased suicidal thoughts, emphasizing the need for targeted therapeutic interventions.

Background

Depressed adolescents and young adults with NSSI are at a heightened risk for suicide, making it crucial to understand the underlying factors contributing to suicidal ideation. Childhood trauma, particularly emotional neglect, has been identified as a significant risk factor for suicidality. This study explores the specific associations between trauma subtypes and suicidal thoughts, focusing on the role of emotion regulation strategies.

Data Highlights

Trauma TypePrevalence
Emotional Neglect68.3%
Emotional Abuse55.8%
Physical Neglect52.5%

Key Findings

  • Emotional neglect, emotional abuse, and physical neglect were the most prevalent trauma types reported.
  • Emotional neglect was positively correlated with suicidal ideation.
  • Cognitive reappraisal was negatively correlated with both emotional neglect and suicidal ideation.
  • Cognitive reappraisal partially mediated the relationship between emotional neglect and suicidal ideation, accounting for 16.9% of the total effect.
  • No significant associations were found for expressive suppression as an emotion regulation strategy.

Clinical Implications

Clinicians should prioritize the assessment of childhood emotional neglect in adolescents with NSSI and depression. Interventions that enhance cognitive reappraisal skills may be beneficial in reducing suicidal ideation in this vulnerable population.

Conclusion

The findings underscore the importance of addressing emotional neglect and improving cognitive reappraisal strategies in therapeutic settings to mitigate suicide risk among depressed youth with NSSI.

Related Resources & Content

  1. BMC Psychiatry (Springer), 2025 -- A review of the scope of non-suicidal self-injury behavior in adolescents with depressive disorders: an analysis of related influencing factors
  2. Frontiers in Psychiatry, 2026 -- Adverse childhood experiences and non-suicidal self-injury in adolescents: the roles of depressive symptoms and teacher care
  3. BMC Psychiatry (Springer), 2025 -- Childhood trauma and recent suicide risk in major depressive disorder: exploring the mediating effect of resilience and cognitive emotion regulation strategies
  4. NICE, 2024 -- Recommendations | Self-harm: assessment, management and preventing recurrence
  5. VA/DoD Clinical Practice Guideline for Assessment and Management of Patients at Risk for Suicide, 2024
  6. BMC Psychiatry (Springer) — Altered cortical structure and networks associated with psychosocial adversity and pain hyposensitivity in adolescents with non-suicidal self-injury
  7. Ask Suicide-Screening Questions (ASQ) Toolkit - National Institute of Mental Health (NIMH)
  8. Recommendations | Self-harm: assessment, management and preventing recurrence | Guidance | NICE
  9. VA/DoD Clinical Practice Guideline for Assessment and Management of Patients at Risk for Suicide
  10. Comparative efficacy and acceptability of psychotherapeutic, pharmacological, and combination treatments for non-suicidal self-injury in children and adolescents: a systematic review and network meta-analysis | BMC Psychiatry | Springer Nature Link
  11. BRAVA: A randomized controlled trial of a brief group intervention for youth with suicidal ideation and their caregivers | Child and Adolescent Psychiatry and Mental Health | Full Text
  12. Management of Suicidal Thoughts and Behaviors in Youth: A Systematic Review | Effective Health Care (EHC) Program
  13. Is emotional regulation related to suicidal thoughts and behaviors in adolescents? A systematic review and three-level meta-analysis of observational studies - Universitat Autònoma de Barcelona Research Portal
  14. Frontiers | Is cognitive emotion regulation mediating effects of childhood maltreatment on suicidal ideation: a cross-sectional retrospective study
  15. Childhood maltreatment and non-suicidal self-injury in adolescent population: A systematic review and meta-analysis - ScienceDirect
  16. Frontiers | Cognitive reappraisal mediated the relationship between childhood emotional neglect and suicidality in depressed adolescents and young adults with NSSI behavior

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