Post-endoscopy gastric cancer in Latin America: a multicentre cohort study from Colombia - Report - MDSpire

Post-endoscopy gastric cancer in Latin America: a multicentre cohort study from Colombia

  • By

  • Hernando Marulanda-Fernandez

  • Juan Sebastián Frías Ordoñez

  • Gilberto Jaramillo Trujillo

  • Julián Parga Bermúdez

  • Jean Sebastián Barrero Gómez

  • Silvia Valentina Monsalve Rico

  • Elder Otero Ramos

  • Lina Otero Parra

  • William Otero-Regino

  • July 8, 2026

  • 0 min

Share

Clinical Report: Gastric Cancer Diagnosed After Endoscopy in Latin America

Overview

This multicenter observational study from Colombia reveals that post-endoscopy gastric cancer (PEGC) accounts for 11.9% of gastric cancer cases diagnosed after a negative endoscopy. PEGC is associated with higher rates of palliative management and increased in-hospital mortality.

Background

Gastric cancer remains a significant global health challenge, with high incidence rates in Latin America, particularly due to factors like Helicobacter pylori infection and socio-environmental conditions. The occurrence of PEGC serves as a critical indicator of endoscopic quality.

Data Highlights

ParameterPEGCNon-PEGC
Frequency11.9% (95% CI: 9.5–14.7)N/A
Helicobacter pylori positivity70.4%67.1%
Palliative management23.9%2.8%
In-hospital mortality16.9%7.0%

Key Findings

  • PEGC was diagnosed in 11.9% of gastric cancer cases in the study cohort.
  • Helicobacter pylori positivity was found in 70.4% of PEGC cases.
  • PEGC cases had a significantly higher rate of palliative management (23.9% vs 2.8%).
  • In-hospital mortality was higher in PEGC cases (16.9% vs 7.0%).

Clinical Implications

The findings emphasize the importance of recognizing PEGC as a quality indicator for endoscopy. Enhanced training and adherence to procedural standards may reduce the incidence of PEGC and improve patient outcomes.

Conclusion

The study highlights the frequency of PEGC in Colombia and its association with poorer clinical outcomes.

Related Resources & Content

  1. Evaluation of Immediate Surgical Results for Rectal Adenocarcinoma Treatment Across 49 Centers in 12 Latin American Countries: A Multicenter Retrospective Study
  2. Gastric Cancer — Detailed histopathological examination of gastric cancer in European and Latin American cohorts uncovers variations in PDL1, HER2, p53, and MUC6 expression levels
  3. Gastric Cancer — Prevalence of CDH1 Germline Variants and the Impact of Dietary Factors in Young Gastric Cancer Patients in Brazil
  4. Tackling Post‐Endoscopy Gastric Cancer in a Low‐Risk Area: Prevalence, Features, and Prevention Opportunities Through Better Clinical Practice
  5. Frontiers in Digital Health — Assessing perceived needs for telepathology implementation in Colombia: a baseline study from Red GLORIA
  6. Performance measures for upper gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative - Update 2025
  7. Tackling Post‐Endoscopy Gastric Cancer in a Low‐Risk Area: Prevalence, Features, and Prevention Opportunities Through Better Clinical Practice - Prat - 2025 - United European Gastroenterology Journal - Wiley Online Library
  8. Article published online: 2025-03-20GuidelineThiemeManagement of epithelial precancerous conditions and

Original Source(s)

Post-endoscopy gastric cancer in Latin America: a multicentre cohort study from Colombia

  • by Hernando Marulanda-Fernandez, Juan Sebastián Frías Ordoñez, Gilberto Jaramillo Trujillo, Julián Parga Bermúdez, Jean Sebastián Barrero Gómez, Silvia Valentina Monsalve Rico, Elder Otero Ramos, Lina Otero Parra, William Otero-Regino

  • July 8, 2026

Related Content

Heterogeneity of immune checkpoint inhibitor-related inflammatory central nervous system adverse event reporting signals in primary and metastatic brain tumors: a pharmacovigilance study with single-cell and spatial transcriptomic contextualization

Predictive value of Ki-67 expression in predicting pathological response to neoadjuvant chemotherapy combined with immunotherapy in lung squamous cell carcinoma

The role of 18F-FDG PET/CT in identifying risk factors for ground-glass nodules in invasive lung adenocarcinoma