Clinical Case: Adult-onset Still’s Disease with Hemorrhagic Pericardial Effusion
Overview
This report presents a rare case of adult-onset Still's disease (AOSD) in a 67-year-old man, characterized by significant hemorrhagic pericardial effusion without the typical rash. The diagnosis was supported by elevated ferritin levels and systemic inflammation.
Background
Adult-onset Still's disease is a rare systemic autoinflammatory disorder that can present with various clinical manifestations, including serosal involvement. The absence of universally accepted biomarkers complicates the diagnosis, which relies on clinical criteria and exclusion of other conditions.
Data Highlights
No numerical data or trial data available in the source material.
Key Findings
['AOSD can present with massive hemorrhagic pericardial effusion without the characteristic rash.', 'Diagnosis relies on clinical manifestations, laboratory findings, and exclusion of other conditions.', 'Elevated serum ferritin and systemic inflammation were observed in the patient.', 'Initial suspicion included tuberculous pericarditis and malignancy, which were ruled out.', 'Glucocorticoid therapy led to rapid resolution of symptoms and serous effusions.']
Clinical Implications
Clinicians should consider AOSD in patients presenting with unexplained serositis, particularly hemorrhagic pericardial effusion. Early recognition and treatment can prevent unnecessary interventions and improve patient outcomes.
Conclusion
This case underscores the importance of considering AOSD in atypical presentations, particularly in the absence of classic symptoms.
