Effect of physical activity on pulmonary function and quality of life in asthma patients: a systematic review and meta-analysis - Report - MDSpire

Effect of physical activity on pulmonary function and quality of life in asthma patients: a systematic review and meta-analysis

  • By

  • Zhicheng Zhu

  • Youjia Mao

  • Yong Fan

  • Zijian Zhu

  • Lisha Xie

  • Cui Huang

  • June 12, 2026

  • 0 min

Share

Clinical Report: Impact of Exercise on Lung Function and Life Quality in Asthma

Overview

This comprehensive review and meta-analysis demonstrate that structured physical activity significantly improves lung function and quality of life in individuals with asthma. Despite these positive findings, the overall certainty of evidence remains low due to risk of bias and heterogeneity among studies.

Background

Asthma is a prevalent chronic respiratory condition that significantly impacts quality of life and can lead to severe health complications. Current pharmacological treatments are often inadequate for symptom control, highlighting the need for effective non-pharmacological interventions. Physical activity has emerged as a promising adjunct therapy, potentially enhancing treatment adherence and overall health outcomes in asthma patients.

Data Highlights

OutcomeMean Difference (MD)95% Confidence Interval (CI)
FEV1% predicted5.791.89–9.69
PEF (L/s)0.470.08–0.85
FVC (L)0.550.25–0.84
PAQLQ1.130.45–1.81

Key Findings

  • Physical activity significantly improved FEV1% predicted, PEF (L/s), FVC (L), and PAQLQ scores.
  • No significant moderators were identified for FEV1% predicted or FVC% predicted outcomes.
  • Twenty-two RCTs involving 1,280 participants were included in the analysis.
  • The certainty of evidence was low for FEV1% predicted and very low for other outcomes.
  • Standardized outcome reporting is needed in future trials to address discrepancies in pulmonary function measurements.

Clinical Implications

Healthcare professionals should consider incorporating structured physical activity into asthma management plans as a non-pharmacological adjunct. Given the variability in response, individualized exercise programs tailored to patient needs may enhance adherence and outcomes.

Conclusion

The findings support the role of physical activity in improving lung function and quality of life for asthma patients, though further research is needed to strengthen the evidence base and standardize outcome measures.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- Comparative efficacy of single exercise interventions on pulmonary function and quality of life in patients with chronic obstructive pulmonary disease: a systematic review and network meta-analysis
  2. Frontiers in Medicine, 2026 -- Comparative efficacy of different types of structured exercise interventions for idiopathic pulmonary fibrosis: a systematic review and meta-analysis
  3. Frontiers in Oncology, 2026 -- Effects of different exercise interventions on quality of life in breast cancer survivors after treatment: a systematic review and network meta-analysis
  4. Microsoft Word - GINA 2025_with figures_tracked for archive_deidentified.docx -- GINA 2025 Report
  5. Frontiers in Psychiatry — Exercise interventions for depressive symptoms in adults with lung and digestive cancer: a meta-analysis of randomized controlled trials
  6. Effects of Physical Exercises in Asthma: An Umbrella Review of Systematic Review and Meta‐Analysis
  7. Microsoft Word - GINA 2025_with figures_tracked for archive_deidentified.docx
  8. J Bras Pneumol. 2025;51(5):e20250009

Original Source(s)

Related Content