Case Report: A seventy-year-stable chest wall bronchogenic cyst with sudden enlargement: coincidence or connection with a concurrent thymic carcinoma? - Report - MDSpire

Case Report: A seventy-year-stable chest wall bronchogenic cyst with sudden enlargement: coincidence or connection with a concurrent thymic carcinoma?

  • By

  • Jiawei Huang

  • Kairen Xie

  • Huajun Li

  • Jing Xie

  • Yunjie Liang

  • Ying Chen

  • Wanli Lin

  • May 8, 2026

  • 0 min

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Clinical Report: Sudden Growth of a Long-Stable Chest Wall Bronchogenic Cyst

Overview

This report details a rare case of a bronchogenic cyst in a 75-year-old woman that exhibited sudden growth after 70 years of dormancy, coinciding with the presence of a thymic carcinoma. Both lesions were surgically excised, and the patient showed favorable recovery without recurrence.

Background

Bronchogenic cysts are congenital anomalies typically found in the mediastinum or lung, often remaining asymptomatic for years. Their enlargement is usually linked to infection or hemorrhage, making this case of delayed growth particularly noteworthy. The concurrent presence of a thymic carcinoma raises questions about potential pathological interactions that warrant further investigation.

Data Highlights

No numerical data was provided in the article.

Key Findings

  • A bronchogenic cyst in the chest wall remained stable for 70 years before sudden growth.
  • The patient presented with a suprasternal lump that increased in size over six months.
  • Histopathological analysis confirmed the chest wall lesion as a bronchogenic cyst and the mediastinal mass as a poorly differentiated squamous cell carcinoma.
  • Both lesions were surgically excised with no signs of recurrence during follow-up.
  • The case suggests a possible pathological link between the bronchogenic cyst and the thymic carcinoma.

Clinical Implications

This case underscores the importance of monitoring chronic masses for changes, as they may indicate underlying malignancies. Clinicians should consider the potential for pathological interactions in cases where distinct lesions are found in close anatomical proximity.

Conclusion

The delayed growth of a bronchogenic cyst after decades of stability, occurring alongside thymic carcinoma, presents a unique clinical scenario that highlights the need for further research into the mechanisms behind such occurrences.

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  2. Drugs - Real World Outcomes, 2016 -- Lung Adenocarcinoma with ALK Rearrangement Manifesting as Carcinoma of Unknown Origin: Implications for Diagnosis and Treatment
  3. Clinical Rheumatology, 2020 -- Exploring Autoimmunity: The Relationship Between Thymoma, Thymectomy, and Systemic Lupus Erythematosus
  4. Bronchogenic Cyst - StatPearls, NCBI Bookshelf
  5. Thymomas and Thymic Carcinomas, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology - PubMed
  6. Frontiers in Oncology — Navigating the Diagnostic Pitfalls of Cystic and Solid Breast Masses: A Comparative Case Report of Metaplastic Carcinoma and Benign Lesions
  7. Bronchogenic Cyst - StatPearls
  8. Thymomas and Thymic Carcinomas, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology
  9. Activity and safety of atezolizumab plus carboplatin and paclitaxel in patients with advanced or recurrent thymic carcinoma (MARBLE): a multicentre, single-arm, phase 2 trial - ScienceDirect

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