Refractory immune cytopenia successfully treated with mycophenolate mofetil in four adolescents with del22q11.2 syndrome - Report - MDSpire

Refractory immune cytopenia successfully treated with mycophenolate mofetil in four adolescents with del22q11.2 syndrome

  • By

  • Cristina Cifaldi

  • Lucia Pacillo

  • Chiara Rossetti

  • Silvia Di Cesare

  • Michele La Manna

  • Veronica Santilli

  • Beatrice Rivalta

  • Elisabetta Lembo

  • Mattia Moratti

  • Lucia Colucci

  • Gigliola Di Matteo

  • Paolo Palma

  • Federica Pulvirenti

  • Emma Concetta Manno

  • Giuseppe Palumbo

  • Donato Amodio

  • Caterina Cancrini

  • May 13, 2026

  • 0 min

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Successful Management of Refractory Immune Cytopenia with Mycophenolate Mofetil

Overview

{'add': 'Specify duration of remission for each patient.'}

Background

{'add': 'List conventional treatments that often fail in this population.'}

Data Highlights

{'edit': "Clarify the definition of 'Stable' for patient 4."}

Key Findings

{'add': 'Include specific immunological assessment methods.'}

Clinical Implications

{'add': 'Suggest specific immunological assessments for treatment individualization.'}

Conclusion

{'edit': 'Emphasize the need for further studies on specific efficacy and safety aspects.'}

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Author(s)/Org, Source, Year -- Title
  3. Author(s)/Org, Source, Year -- Title
  4. Author(s)/Org, Source, Year -- Title
  5. The systemic effects of 22q11.2 deletion syndrome on immunity - PubMed
  6. ASH CLINICAL PRACTICE GUIDELINES
  7. Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia - PubMed
  8. The systemic effects of 22q11.2 deletion syndrome on immunity - PubMed
  9. ASH CLINICAL PRACTICE GUIDELINES
  10. Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia - PubMed

Original Source(s)

Refractory immune cytopenia successfully treated with mycophenolate mofetil in four adolescents with del22q11.2 syndrome

  • by Cristina Cifaldi, Lucia Pacillo, Chiara Rossetti, Silvia Di Cesare, Michele La Manna, Veronica Santilli, Beatrice Rivalta, Elisabetta Lembo, Mattia Moratti, Lucia Colucci, Gigliola Di Matteo, Paolo Palma, Federica Pulvirenti, Emma Concetta Manno, Giuseppe Palumbo, Donato Amodio, Caterina Cancrini

  • May 13, 2026

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