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Identifying Risk Factors for Allergic Rhinitis in Pediatric Populations: A Comprehensive Review of Systematic Reviews and Meta-Analyses

  • By

  • Yuzhu Dou

  • Jinyi Li

  • Xueyan Qiu

  • Pengchen Wu

  • Yaqi Wang

  • Mei Chen

  • Zhengjiu Cui

  • Fei Luo

  • Siming Zhai

  • Tao Li

  • Qigang Dai

  • Bin Yuan

  • September 7, 2026

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Clinical Report: Identifying Risk Factors for Allergic Rhinitis in Pediatric Populations

Overview

This comprehensive review identifies 75 risk factors associated with allergic rhinitis (AR) in children, highlighting 22 factors linked to increased risk and 7 considered protective. The overall quality of evidence was assessed using GRADE, indicating that it is low, with only one factor supported by moderate-quality evidence.

Background

Allergic rhinitis is a prevalent chronic condition affecting children, leading to significant health and economic burdens. Understanding the risk factors associated with AR is crucial for developing targeted prevention strategies. The evidence base for these factors has been fragmented, necessitating a systematic review to consolidate findings and assess methodological quality.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • Identified 75 risk factors for allergic rhinitis in children.
  • 22 factors associated with increased risk, including early-life antibiotic use and cesarean section.
  • 7 protective factors identified, such as pet exposure and consumption of raw milk.
  • Only one factor, early-life food sensitization, supported by moderate-certainty evidence.
  • Overall evidence quality was low or very low for most factors.

Clinical Implications

The findings indicate a need for more rigorous studies to validate the identified risk factors for allergic rhinitis in children. Clinicians should consider these factors when assessing risk and developing prevention strategies.

Conclusion

This umbrella review provides a comprehensive overview of risk factors for pediatric allergic rhinitis, emphasizing the need for further research to enhance the evidence base.

Related Resources & Content

  1. JAMA Pediatrics, 2023 -- Risk Factors for the Development of Food Allergy in Infants and Children: A Systematic Review
  2. MDSpire News, 2023 -- Pediatric Allergic Rhinitis: When Meds Fall Short
  3. Frontiers in Pediatrics, 2023 -- Health-related quality of life and its determinants in children with allergic rhinitis
  4. mdspire news, 2023 -- Major Food Allergy Risks Clarified
  5. Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part II—Guidelines on Oral and Ocular Treatments
  6. Prevalence and risk factors of allergic rhinitis in Chinese children: a systematic review and meta-analysis | BMC Pediatrics | Springer Nature Link
  7. Frontiers, 2023 -- Risk factors for allergic rhinitis in children: an umbrella review of systematic review and meta-analysis
  8. Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part II—Guidelines on Oral and Ocular Treatments
  9. Prevalence and risk factors of allergic rhinitis in Chinese children: a systematic review and meta-analysis | BMC Pediatrics | Springer Nature Link
  10. Frontiers | Risk factors for allergic rhinitis in children: an umbrella review of systematic review and meta-analysis

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