Opioid Prescribing Trends After Guidelines - Report - MDSpire

Opioid Prescribing Trends After Guidelines

  • By

  • Kathryn Wighton

  • March 27, 2026

  • 2 min

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Clinical Report: Opioid Prescribing Trends After Guidelines

Overview

A retrospective analysis of 25,076 patients undergoing parotidectomy revealed a significant decrease in opioid prescribing and an increase in nonopioid prescribing following the 2021 clinical practice guidelines. This trend indicates a shift towards multimodal analgesia in postoperative care.

Background

The opioid crisis has prompted healthcare professionals to reevaluate pain management strategies, particularly in surgical settings. The 2021 guidelines from the American Academy of Otolaryngology–Head and Neck Surgery advocate for a nonopioid-first approach, emphasizing the importance of multimodal analgesia. Understanding the impact of these guidelines on prescribing patterns is crucial for improving patient outcomes and reducing opioid dependency.

Data Highlights

MetricPre-GuidelinePost-Guideline
Opioid Prescribing46%Decreased by 7.44%
Nonopioid Prescribing7%Increased by 3.73%
Patients without Opioids47%Increased

Key Findings

  • Opioid prescribing decreased by 7.44% immediately after guideline publication.
  • Nonopioid prescribing increased by 3.73% immediately following the guidelines.
  • Opioid prescribing continued to decline by 0.20% every 3 months post-guideline.
  • Nonopioid prescribing continued to rise by 0.12% every 3 months after the guidelines were implemented.
  • Statistically significant differences were observed in prescribing patterns before and after guideline implementation.
  • Trends in opioid prescribing began to decline prior to the guideline publication, indicating earlier efforts to reduce opioid use.

Clinical Implications

Clinicians should consider adopting the nonopioid-first approach in postoperative pain management to align with current guidelines. Continuous monitoring of prescribing patterns is essential to ensure adherence to these recommendations and to mitigate the risk of opioid dependency among patients.

Conclusion

The study highlights a successful shift in prescribing practices following the implementation of updated guidelines, demonstrating the feasibility of reducing opioid use while increasing nonopioid alternatives in postoperative care.

References

  1. Pain Medicine, 2023 -- Association of opioid tapering with pain-related emergency department visits, hospitalizations, and primary care visits: a retrospective cohort study
  2. conexiant, 2023 -- Tracking Opioid Refills After Surgery
  3. The ASCO Post, 2017 -- EXPECT QUESTIONS ABOUT THE RISK OF OPIOID ADDICTION
  4. Drugs - Real World Outcomes, 2021 -- An Extensive Observational Analysis of Trends and Risk Factors Associated with Opioid Overdose: Insights from Real-World Data for Improved Opioid Prescribing
  5. Clinical Practice Guideline, 2021 -- Opioid Prescribing for Analgesia After Common Otolaryngology Operations Executive Summary
  6. Evaluation of Opioid Prescribing Guidelines on Opioid Prescription Trends for Parotidectomy, 2023 -- UTMB Health Research Expert Profiles
  7. Clinical Practice Guideline: Opioid Prescribing for Analgesia After Common Otolaryngology Operations
  8. Evaluation of Opioid Prescribing Guidelines on Opioid Prescription Trends for Parotidectomy
  9. Randomized control trial of opioid- versus nonopioid-based analgesia after thyroidectomy - PubMed

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