Recurrent Cardiac Arrests from Pulseless Electrical Activity Linked to Coronary Vasospasm in the Absence of Obstructive Coronary Artery Disease
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July 7, 2026
Clinical Report: Recurrent Cardiac Arrests from Pulseless Electrical Activity Linked to Coronary Vasospasm
Overview
This case report details recurrent pulseless electrical activity arrests in a postoperative patient attributed to coronary vasospasm. The diagnosis was supported by transient ischemic ECG changes, nonobstructive coronary angiography, and rapid improvement with vasodilator therapy.
Background
Coronary vasospasm is a significant but often overlooked cause of myocardial ischemia and cardiac arrest, particularly in postoperative and critically ill patients. Its presentation can be subtle, often misattributed to other conditions, making early recognition crucial.
Data Highlights
No numerical data or trial data presented in the article.
Key Findings
- Coronary vasospasm can mimic acute coronary syndromes and lead to life-threatening instability.
- Transient ischemic ECG changes and absence of obstructive coronary disease are key indicators for diagnosis.
- Vasospasm is highly reversible with appropriate vasodilator therapy.
- Invasive coronary functional testing is the gold standard but often contraindicated in unstable patients.
Clinical Implications
Clinicians should maintain a high index of suspicion for coronary vasospasm in postoperative patients presenting with cardiac instability.
Conclusion
This case highlights the importance of recognizing coronary vasospasm as a potential cause of cardiac arrest in critically ill patients.
Related Resources & Content
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- Critical Care (Springer) -- Neurological Outcomes in Out-of-Hospital Cardiac Arrest: Analyzing State-Transition Patterns Beyond Myocardial Function
- Clinical Research in Cardiology -- Right ventricular dysfunction: an overlooked predictor of sudden cardiac death and arrhythmic events—a meta-analysis
- 2024 ESC Guidelines for the management of chronic coronary syndromes | European Heart Journal | Oxford Academic
- 2024 ESC Guidelines for the management of chronic coronary syndromes
- Clinical characteristics and long-term prognosis of vasospastic angina patients who survived out-of-hospital cardiac arrest: multicenter registry study of the Japanese Coronary Spasm Association - PubMed
- 2024 ESC Guidelines for the management of chronic coronary syndromes | European Heart Journal | Oxford Academic
- 2024 ESC Guidelines for the management of chronic coronary syndromes
- Clinical characteristics and long-term prognosis of vasospastic angina patients who survived out-of-hospital cardiac arrest: multicenter registry study of the Japanese Coronary Spasm Association - PubMed
Based on findings from:
Recurrent Pulseless Electrical Activity Arrests Due to Coronary Vasospasm Without Obstructive Coronary Artery Disease
Annals Of Internal Medicine: Clinical Cases, 2026.
https://www.acpjournals.org/doi/10.7326/aimcc.2026.0047
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