Harmonic analysis of radial pulse in traditional Chinese medicine: physiological alterations associated with hepatitis B and hepatitis C infections - Report - MDSpire

Harmonic analysis of radial pulse in traditional Chinese medicine: physiological alterations associated with hepatitis B and hepatitis C infections

  • By

  • Chung-Hung Wu

  • Kuan-Fu Liao

  • Jian-Jung Chen

  • Hsientsai Wu

  • July 8, 2026

  • 0 min

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Clinical Report: Harmonic Assessment of Radial Pulse in Hepatitis Infections

Overview

This study explores the relationship between harmonic analysis of radial pulse signals and physiological changes in patients with hepatitis B and C infections.

Background

Hepatitis B and C infections are major global health concerns, leading to severe liver complications. Current diagnostic methods often involve invasive procedures, which can deter patients from seeking screening.

Data Highlights

GroupC1 Value (Mean ± SD)p-value
HCV529.09 ± 57.990.047
HBV503.65 ± 64.510.481
Healthy Controls477.78 ± 100.49

Key Findings

  • The first harmonic component (C1) showed significant differences among healthy controls, HBV, and HCV groups (p = 0.014).
  • HCV patients had significantly higher C1 values compared to healthy controls (p = 0.047).
  • No significant difference was found between HBV and HCV groups (p = 0.098).
  • Exploratory logistic regression indicated an independent association between C1 and HCV infection status (OR = 1.008, p = 0.047).

Clinical Implications

The findings indicate that harmonic analysis of radial pulse may serve as a non-invasive diagnostic tool for assessing physiological changes in patients with hepatitis infections. Further research is necessary to validate these observations and explore their clinical significance.

Conclusion

Alterations in the first harmonic component of radial pulse waveforms may reflect physiological changes in chronic viral hepatitis, particularly in HCV infection.

Related Resources & Content

  1. Complement 5a as a Biomarker for Advanced Fibrosis and Early Cirrhosis in Chronic Hepatitis B Virus Infection, Infection, 2016
  2. Radial pulse harmonic analysis for cardiometabolic assessment: a computational and translational mini review, Frontiers in Endocrinology, 2026
  3. Association between red cell distribution width and HBV viral load and liver function parameters in patients with chronic hepatitis B: a real-world data study, Frontiers in Medicine, 2026
  4. Consolidated guidelines on hepatitis B and C prevention, testing, treatment, service delivery and monitoring, WHO, 2026
  5. Noninvasive Assessment of Liver Fibrosis | New England Journal of Medicine, 2025
  6. Journal of Gastroenterology — The Impact of Hypothyroidism on Liver Fibrosis Severity
  7. Consolidated guidelines on hepatitis B and C prevention, testing, treatment, service delivery and monitoring
  8. Noninvasive Assessment of Liver Fibrosis | New England Journal of Medicine
  9. Frontiers | Association of estimated pulse wave velocity with cardiovascular disease outcomes and all-cause death—a systematic review and meta-analysis

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