EGS-Net: a knowledge-augmented machine learning framework for predicting future high-myopia risk from longitudinal school-screening trajectories - Report - MDSpire

EGS-Net: a knowledge-augmented machine learning framework for predicting future high-myopia risk from longitudinal school-screening trajectories

  • By

  • Zhan Tang

  • Na Zhao

  • Zhaoyu Huang

  • Jinhao Lu

  • Chao Dai

  • Jian Wang

  • Runze Zheng

  • June 25, 2026

  • 0 min

Share

Clinical Report: EGS-Net: An Enhanced Machine Learning Approach for Forecasting High-Myopia Risk

Overview

This study presents the EGS predictive framework, which utilizes longitudinal school screening data to improve the prediction of high-myopia risk in children. The model demonstrated high recall and precision.

Background

The increasing prevalence of myopia, particularly high myopia, poses significant public health challenges. Early detection and intervention are critical to prevent the progression of myopia and associated complications. Traditional screening methods often fall short, necessitating innovative approaches like machine learning to enhance predictive accuracy.

Data Highlights

The EGS framework achieved a Recall of 0.9533 and Precision of 0.9211, with an AUC of 0.9992 for the AdaBoost model.

Key Findings

  • The EGS model integrates a multi-model ensemble architecture with a clinical risk-heuristic override module.
  • Longitudinal refractive trajectories were critical for improving model interpretability and prediction accuracy.
  • High Recall and Precision metrics indicate the model's potential for reliable future-risk identification.
  • 5-fold cross-validation was employed for model tuning and evaluation.
  • SHAP analysis confirmed the importance of longitudinal features in the model.

Clinical Implications

The EGS framework offers a scalable solution for school-based myopia surveillance, prioritizing high-risk recall to facilitate timely clinical interventions.

Conclusion

The EGS predictive framework represents a significant advancement in the use of machine learning for myopia risk assessment.

Related Resources & Content

  1. npj Digital Medicine, 2025 -- Personalized Predictions and Interventions for Myopia Progression Using AI Technology
  2. Frontiers in Medicine, 2026 -- Interocular asymmetry and ocular biometric patterns in pediatric high myopia: implications for early risk stratification
  3. Eyecare Business, 2024 -- Optometric Business Tracker
  4. IMI, 2025 -- Interventions for Controlling Myopia Onset and Progression 2025 - PMC
  5. Contact Lens Spectrum — Myopia Beyond 2025
  6. De Novo Classification Request for Essilor® Stellest®
  7. Vision and hearing screening for school-age children: implementation handbook
  8. IMI—Interventions for Controlling Myopia Onset and Progression 2025 - PMC

Original Source(s)

Related Content