Correction: Neurological manifestations of SARS-CoV-2 infection: protocol for a sub-analysis of the COVID-19 critical care consortium observational study - Report - MDSpire

Correction: Neurological manifestations of SARS-CoV-2 infection: protocol for a sub-analysis of the COVID-19 critical care consortium observational study

  • By

  • Denise Battaglini

  • Lavienraj Premraj

  • Matthew Griffee

  • Samuel Huth

  • Jonathon Fanning

  • Glenn Whitman

  • Diego Bastos Porto

  • Rakesh Arora

  • Lucian Durham

  • Eric Gnall

  • Marcelo Amato

  • Virginie Williams

  • Alexandre Noel

  • Sabrina Araujo De Franca

  • Gordan Samoukovic

  • Bambang Pujo

  • David Kent

  • Eva Marwali

  • Abdulrahman Al-Fares

  • Stephanie-Susanne Stecher

  • Mauro Panigada

  • Marco Giani

  • Giuseppe Foti

  • Paolo Pelosi

  • Antonio Pesenti

  • Nicole Marie White

  • Gianluig Li Bassi

  • Jacky Suen

  • John F. Fraser

  • Chiara Robba

  • Sung-Min Cho

  • May 1, 2026

  • 0 min

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Correction: Neurological Effects Associated with SARS-CoV-2 Infection

Overview

This report addresses a correction made to the classification of the modified Rankin Scale (mRS) domains in the original article on neurological effects of SARS-CoV-2 infection. The updated figure has been provided to enhance clarity and accuracy in the study's findings.

Background

Neurological manifestations of SARS-CoV-2 infection are increasingly recognized, with symptoms ranging from anosmia to more severe complications like encephalopathy. Understanding these effects is crucial for managing patients with COVID-19, particularly in critical care settings. Accurate classification and reporting of neurological outcomes are essential for guiding treatment and rehabilitation strategies.

Data Highlights

The original version of this article has been updated with a corrected figure.

Key Findings

  • The modified Rankin Scale (mRS) domains were incorrectly classified in the original publication.
  • Neurological complications in COVID-19 patients include a range of symptoms, highlighting the need for comprehensive neurological assessments.
  • Microthrombi and acute infarcts have been documented in neuropathological studies of COVID-19 patients.
  • Current guidelines emphasize the importance of recognizing both acute and post-acute neurological involvement in COVID-19.
  • Multidisciplinary rehabilitation planning is recommended for patients with persistent neurological deficits.

Clinical Implications

Healthcare professionals should be aware of the neurological complications associated with COVID-19 and the importance of accurate assessment tools like the mRS. Implementing routine screening and rehabilitation strategies can improve patient outcomes in critical care settings.

Conclusion

The correction of the mRS classification underscores the importance of accurate reporting in neurological research related to COVID-19. Continued vigilance and updated protocols are essential for effective patient management.

References

  1. Battaglini, D. et al., Front. Med., 2022 -- Correction: Neurological Effects Associated with SARS-CoV-2 Infection
  2. Acta Neuropathologica — Factors Associated with Critical Illness-Related Encephalopathy in Postmortem Neuropathology of COVID-19
  3. Acta Neuropathologica — Emerging Neuropathological Features in COVID-19: Insights into Microvascular Damage and Hypoxic Injury
  4. Clinical management of COVID-19: living guideline, June 2025 - World Health Organization (WHO)
  5. Long COVID Clinical Guidance | Long COVID | CDC
  6. Acta Neuropathologica — Neuropathological Insights in Down Syndrome, Alzheimer’s Disease, and Control Subjects with and without SARS-CoV-2: Initial Observations
  7. Infection — Minimal Neurocognitive Effects of COVID-19 Across Different Age Groups and Severity Levels: A Multicenter Study on Biomarkers in Adult and Pediatric Patients with Acute Respiratory Infections, Both SARS-CoV-2 Positive and Negative
  8. Clinical management of COVID-19: living guideline, June 2025 - World Health Organization (WHO)
  9. Long COVID Clinical Guidance | Long COVID | CDC
  10. Association between SARS-CoV-2 and stroke: perspectives from a metaumbrella-review | BMC Neurology | Springer Nature Link

Original Source(s)

Correction: Neurological manifestations of SARS-CoV-2 infection: protocol for a sub-analysis of the COVID-19 critical care consortium observational study

  • by Denise Battaglini, Lavienraj Premraj, Matthew Griffee, Samuel Huth, Jonathon Fanning, Glenn Whitman, Diego Bastos Porto, Rakesh Arora, Lucian Durham, Eric Gnall, Marcelo Amato, Virginie Williams, Alexandre Noel, Sabrina Araujo De Franca, Gordan Samoukovic, Bambang Pujo, David Kent, Eva Marwali, Abdulrahman Al-Fares, Stephanie-Susanne Stecher, Mauro Panigada, Marco Giani, Giuseppe Foti, Paolo Pelosi, Antonio Pesenti, Nicole Marie White, Gianluig Li Bassi, Jacky Suen, John F. Fraser, Chiara Robba, Sung-Min Cho

  • May 1, 2026

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