Prevalence of neurocognitive dysfunction and associated risk factors among follow-up diabetic type 2 patients in diabetes center of Al-Thawra hospital, Sana’a, Yemen - Report - MDSpire

Prevalence of neurocognitive dysfunction and associated risk factors among follow-up diabetic type 2 patients in diabetes center of Al-Thawra hospital, Sana’a, Yemen

  • By

  • Aisha A. Saber

  • Ahmed M. Al-Ghani

  • Abdulrahman A. Humaid

  • July 16, 2026

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Clinical Report: Assessment of Neurocognitive Impairment in Type 2 Diabetes

Overview

This study reports a 43% prevalence of neurocognitive dysfunction among type 2 diabetes patients in Yemen. Significant associations were found between neurocognitive impairment and factors such as age, education level, employment status, and duration of diabetes.

Background

Type 2 diabetes mellitus (T2DM) is a chronic condition that can lead to various complications, including cognitive decline.

Data Highlights

CharacteristicPrevalence (%)
Neurocognitive Dysfunction43
Male Patients54.75
Female Patients45.25

Key Findings

  • 43% prevalence of neurocognitive dysfunction among T2DM patients.
  • Higher prevalence in elderly patients, low-educated individuals, and those who are unemployed.
  • Significant association between longer duration of diabetes and increased neurocognitive dysfunction.
  • Lower BMI and regular exercise correlated with decreased neurocognitive dysfunction.
  • Statistical significance (P-value < 0.001) for age, education, employment, and diabetes duration.

Clinical Implications

Healthcare providers should consider regular cognitive assessments for T2DM patients, particularly those who are older, less educated, or unemployed. Encouraging lifestyle modifications such as exercise may help mitigate cognitive decline.

Conclusion

The findings indicate a prevalence of neurocognitive dysfunction in T2DM patients.

Related Resources & Content

  1. Frontiers in Endocrinology, 2026 -- Sentinel factors for mild cognitive impairment in type 2 diabetes mellitus and their interaction mechanisms: a narrative review with network analysis perspective
  2. Frontiers in Endocrinology, 2026 -- Diabetes-related stigma among individuals with type 1 diabetes in Jazan, Saudi Arabia: sociodemographic and clinical correlates
  3. Frontiers in Endocrinology, 2026 -- Exploring Gender Disparities in Diabetes Awareness, Glycemic Management, and Cardiovascular Risk in Adults with Type 2 Diabetes: A Cross-Sectional Analysis
  4. The Journal of Clinical Endocrinology & Metabolism -- Development and Validation of a Cognitive Risk Assessment Tool for Middle-aged and Older Adults with Type 2 Diabetes: A Cross-Sectional Analysis
  5. American Diabetes Association, 2026 -- Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Care in Diabetes
  6. 4. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Care in Diabetes—2026 | Diabetes Care | American Diabetes Association
  7. Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy - PubMed
  8. Associations of glycaemia‐related risk factors with dementia and cognitive decline in individuals with type 2 diabetes: A systematic review and meta‐analysis - PMC

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