Temporal trends and disparities in heat-related cardiovascular mortality in the United States (1999–2024): a CDC WONDER analysis - Report - MDSpire

Temporal trends and disparities in heat-related cardiovascular mortality in the United States (1999–2024): a CDC WONDER analysis

  • By

  • Hassaan Abid

  • Gaaitri Lohano

  • Muhammad Vazaym

  • Muhammad Jawad

  • Rimsha Adnan

  • Muhammad Mohid Haroon

  • June 24, 2026

  • 0 min

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Trends and Inequities in Cardiovascular Deaths Linked to Heat Exposure in the U.S.

Overview

This study analyzes national trends in heat-related cardiovascular mortality in the U.S. from 1999 to 2024, revealing significant increases in mortality rates, particularly among males and Hispanic populations.

Background

Heat exposure is increasingly recognized as a significant public health concern, particularly for individuals with pre-existing cardiovascular conditions. Rising global temperatures and extreme heat events can exacerbate cardiovascular complications, leading to increased mortality.

Data Highlights

YearMortality Rate (AAMR per 100,000)
1999-2004Decline
2015-2024Increase (APC: 17.58%; p < 0.001)

Key Findings

  • A total of 10,731 deaths were identified as heat-related cardiovascular mortality.
  • Significant decline in mortality rates was observed from 1999 to 2004.
  • From 2015 to 2024, there was a statistically significant increase in mortality rates (APC: 17.58%; p < 0.001).
  • Males experienced a significant overall increase in mortality (AAPC: 3.64%; p = 0.034).
  • Hispanic populations showed increases in mortality rates.
  • The Western and Southern U.S. regions exhibited the highest burden of heat-related cardiovascular mortality.

Clinical Implications

Healthcare professionals should be aware of the increasing risk of cardiovascular mortality associated with heat exposure, particularly in vulnerable populations.

Conclusion

The study highlights the rising trend of heat-related cardiovascular mortality in the U.S. and the observed disparities across different demographics and regions.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Trends and Inequities in Cardiovascular Deaths Linked to Heat Exposure in the U.S.
  2. European Journal of Preventive Cardiology — Incidence and burden of cardiovascular disease attributable to extreme heat in China
  3. European Journal of Preventive Cardiology — Guidelines for Engaging in Physical Activity During Hot Weather for Adults with Cardiovascular Disease
  4. Frontiers in Cardiovascular Medicine — Opioid overdose and cardiovascular disease-related mortality: a retrospective analysis using real-world data from the USA, 1999–2023
  5. Journal of General Internal Medicine (Springer) — Upstream Drivers of Poor Cardiovascular Health Among Black and White Americans
  6. Heat–health action plans: guidance, second edition
  7. Clinical Overview of Heat and Cardiovascular Disease | Heat Health | CDC
  8. Clinical Guidance for Heat Health | Heat Health | CDC
  9. Heat-related Illnesses | Heat | CDC
  10. Heat- and Cold-Related Mortality Burden in the US From 2000 to 2020 | Environmental Health | JAMA Network Open | JAMA Network
  11. Study Finds Higher Cardiac Deaths in Combined Day-Night Heatwaves - American College of Cardiology
  12. Disparities in County-Level Vulnerability to Cardiovascular Mortality Associated With Extreme Heat Exposure | JACC: Advances
  13. Meta-analysis of heat-induced changes in cardiac function from over 400 laboratory-based heat exposure studies | Nature Communications
  14. Sex differences in the impact of extreme heat on cardiovascular disease outcomes: a systematic review and meta-analysis - PMC

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