Clinical Report: Association of HALP Score with Early Neurological Decline in AIS

Overview

This study investigates the relationship between the hemoglobin-albumin-lymphocyte-platelet (HALP) score and early neurological deterioration (END) in acute ischemic stroke (AIS) patients. A lower HALP score was found to be an independent predictor of END.

Background

Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality, with early neurological deterioration (END) being a significant complication that can worsen outcomes. Identifying risk factors for END is crucial for improving patient management and outcomes. The HALP score, which integrates several biomarkers, may provide a more comprehensive assessment of risk in AIS patients.

Data Highlights

Key Findings

• 31.3% of patients developed early neurological deterioration (END).
• Independent predictors of END included lower HALP score, elevated NIHSS score, and LAA subtype.
• The HALP score remained significant after adjusting for demographic and treatment-related variables.
• A nomogram incorporating HALP score, LAA subtype, and NIHSS score showed moderate discrimination for predicting END.

Clinical Implications

The HALP score may serve as a valuable tool for early risk assessment in patients with acute ischemic stroke. Clinicians should consider incorporating this score into their evaluation to identify patients at higher risk for early neurological deterioration.

Conclusion

A lower HALP score was associated with increased risk of early neurological deterioration in AIS patients.

Related Resources & Content

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