Medication Abortion Provision by Advance Practice Clinicians and Abortion Completeness - Report - MDSpire

Medication Abortion Provision by Advance Practice Clinicians and Abortion Completeness

  • By

  • Sarah Averbach

  • Michelle Luneau

  • Sheila K. Mody

  • Gennifer Kully

  • Nicole E. Johns

  • Vedavati Patwardhan

  • Antoinette M. Marengo

  • July 17, 2026

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Provision of Medication Abortions by Advanced Practice Clinicians and Assessment of Abortion Outcomes

Overview

This study evaluates the effectiveness and safety of medication abortions (MABs) provided by advanced practice clinicians (APCs) compared to physicians. Findings indicate that APCs achieve effectiveness rates of 92.9% (95% CI, 92.6% to 93.2%) and similar adverse event profiles.

Background

The provision of medication abortions by advanced practice clinicians has become increasingly relevant following regulatory changes by the FDA. With 26 states enforcing physician-only laws, understanding the outcomes of APC-provided MABs is critical for policy and practice. This study addresses the gap in data regarding the effectiveness and safety of MABs administered by APCs.

Data Highlights

Provider TypeEstimated EffectivenessAdverse Events
APCs92.9% (95% CI, 92.6% to 93.2%)0.2% ED visits
Physicians90.1% (95% CI, 87.1% to 93.0%)0.1% AEs

Key Findings

  • APCs provided 58,473 out of 59,150 MABs in the study.
  • Estimated effectiveness for APCs was 92.9%, while for physicians it was 90.1%.
  • Adverse events were low and did not differ significantly between APCs and physicians.
  • Follow-up rates were similar across both clinician types.

Clinical Implications

The findings indicate that APCs can provide medication abortions with effectiveness and safety outcomes comparable to those of physicians.

Conclusion

The study concludes that APCs can provide medication abortions with outcomes comparable to those of physicians.

Related Resources & Content

  1. JAMA Network, JAMA Network Open, 2025 -- Medication Abortion Provision by Advance Practice Clinicians and Abortion Completeness
  2. Journal of Medical Internet Research (JMIR) — Perceived Importance of Abortion Care Features and Access to Telehealth Technologies Among Medication Abortion Patients by Abortion Care Model: Cross-Sectional Analysis of a Prospective Cohort Study
  3. JAMA Network Open — Abortion Bans and Pregnancy-Related Care Across Physician Specialties: A Qualitative Study
  4. JAMA Network Open — Mexico-Based Accompaniment Collectives for Abortion in the US After Dobbs
  5. Stat News — Telehealth abortion with mifepristone continues, with backup plans still in place
  6. WHO Abortion Care Guideline, 2nd ed
  7. Increasing Access to Abortion | ACOG
  8. Medication Abortion Provision by Advance Practice Clinicians and Abortion Completeness | Obstetrics and Gynecology | JAMA Network Open | JAMA Network
  9. Society of Family Planning Clinical Recommendation: Management of undesired pregnancy of unknown location and abortion at less than 42 days of gestation - PubMed
  10. Society of Family Planning: Prevention of infection after abortion and pregnancy loss
  11. Guttmacher Releases First-Ever State-Level Data on Medication Abortion Provision | Guttmacher Institute

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