Clinical Report: Assessment of Retinal Layer Thickness Above PHOMS

Overview

This study evaluates the use of optical coherence tomography (OCT) to differentiate between true papilloedema and pseudo-papilloedema by measuring the thickness of retinal layers above peripapillary hyperreflective ovoid mass-like structures (PHOMS). Findings suggest that PHOMS UP thickness is significantly greater in true papilloedema compared to pseudo-papilloedema, indicating potential for a rapid diagnostic tool.

Background

Differentiating between true and pseudo-papilloedema is critical due to their differing clinical implications and management strategies. True papilloedema can indicate serious underlying conditions, while pseudo-papilloedema is often benign. The ability to accurately assess these conditions using non-invasive OCT could enhance clinical decision-making and patient outcomes.

Data Highlights

No numerical data available in the provided material.

Key Findings

• PHOMS are associated with various optic nerve head disorders and can indicate either pseudo-papilloedema or true papilloedema.
• Types 1 and 2 PHOMS are indicative of pseudo-papilloedema, while type 3 is associated with true papilloedema.
• The study hypothesized that PHOMS UP thickness would be greater in true papilloedema than in pseudo-papilloedema.
• Accurate differentiation between these conditions is crucial for appropriate management and treatment.
• OCT serves as a non-invasive tool for assessing retinal layer thickness and aiding in the diagnosis of papilloedema types.

Clinical Implications

The findings support the use of OCT measurements to differentiate between true and pseudo-papilloedema, potentially allowing for quicker and more accurate diagnoses in clinical settings. This could lead to improved management strategies for patients presenting with optic nerve head abnormalities.

Conclusion

Suggest specific areas for future research to solidify the role of OCT in clinical assessments.

Related Resources & Content

1. Frontiers in Neurology, 2026 -- Retinal Layer Reflectivity and Thickness as OCT Biomarkers for Diagnosis and Imaging-Based Stratification Relative to the 4.5-Hour Window in Acute Central Retinal Artery Occlusion
2. Retinal Physician, 2015 -- Appropriate Interpretation of OCT Imaging
3. Glaucoma Physician, 2019 -- Understanding Optical Coherence Tomography Angiography in Glaucoma
4. Optometric Management, 2024 -- Identifying diabetic retinopathy biomarkers with OCT
5. Frontiers, 2024 -- Peripapillary hyperreflective ovoid mass-like structures: multimodal imaging and associated diseases
6. Scientific Reports, 2025 -- Optical coherence tomography surpasses fundus imaging and intracranial pressure measurement in monitoring idiopathic intracranial hypertension
7. Eye, 2024 -- Association of optic disc drusen and small scleral canals – A systematic review and meta-analysis
8. Frontiers | Peripapillary hyperreflective ovoid mass-like structures: multimodal imaging and associated diseases
9. Optical coherence tomography surpasses fundus imaging and intracranial pressure measurement in monitoring idiopathic intracranial hypertension | Scientific Reports
10. Association of optic disc drusen and small scleral canals – A systematic review and meta-analysis | Eye