Assessment of the Frequency of Psychological Comorbidities and Their Impact on Injection Therapy Results in Individuals with Chronic Low Back Pain: A Retrospective Cohort Analysis Using Registry Data - Report - MDSpire

Assessment of the Frequency of Psychological Comorbidities and Their Impact on Injection Therapy Results in Individuals with Chronic Low Back Pain: A Retrospective Cohort Analysis Using Registry Data

  • By

  • Anas Afifi

  • Khaled Allan

  • Marc Brügmann

  • Andrea Roth-Daniek

  • Rolf Sobottke

  • Moh’d Yazan Khasawneh

  • Koroush Kabir

  • Alba Shehu

  • Michel Teuben

  • Ümit Mert

  • Maher Ghandour

  • Mohamad Agha Mahmoud

  • April 28, 2026

  • 0 min

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Assessment of Psychological Comorbidities in Chronic Low Back Pain Patients

Overview

This study reveals a high prevalence of psychological comorbidities among patients with chronic low back pain (CLBP) and their significant impact on treatment outcomes. Specifically, patients with depression, anxiety, and chronic pain disorder exhibited greater pain severity and less improvement following injection therapy.

Background

Chronic low back pain is a leading cause of disability and significantly affects quality of life. Psychological comorbidities, such as depression and anxiety, are prevalent in this population and can exacerbate pain perception and hinder treatment efficacy. Understanding these associations is crucial for developing effective, multidisciplinary management strategies.

Data Highlights

{'anxiety': '28-31% (specify if from different assessments)', 'chronic_pain_disorder': 'Include diagnostic criteria or context for the 17.1% prevalence.'}

Key Findings

{'statistical_significance': 'Add p-values for anxiety and chronic pain disorder comparisons.'}

Clinical Implications

{'integration': 'Suggest specific psychological assessments or therapies to be included.'}

Conclusion

Psychological comorbidities are prevalent in CLBP patients and significantly affect treatment responses. Addressing these factors is essential for improving patient care and outcomes.

References

  1. Author(s)/Org, Source, Year -- Title
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  5. Practice Guideline: Do Not Use Injections or Radiofrequency to Treat Chronic Cervical Spine or Low Back Pain | AAFP
  6. Diagnosis and Treatment of Low Back Pain (LBP) (2022) - VA/DOD Clinical Practice Guidelines
  7. Practice Guideline: Do Not Use Injections or Radiofrequency to Treat Chronic Cervical Spine or Low Back Pain | AAFP
  8. Diagnosis and Treatment of Low Back Pain (LBP) (2022) - VA/DOD Clinical Practice Guidelines

Original Source(s)

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