Blind nasoenteric tube insertion using a pharmaco-mechanical synergy protocol in frail older adults with chronic wounds: a retrospective study - Report - MDSpire

Blind nasoenteric tube insertion using a pharmaco-mechanical synergy protocol in frail older adults with chronic wounds: a retrospective study

  • By

  • Doudou Zhang

  • Qiuping Zhang

  • Xiling Xiao

  • Hongmin Luo

  • Huining Bian

  • Wen Lai

  • Pingyun Chen

  • June 24, 2026

  • 0 min

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Clinical Report: Evaluation of a Pharmaco-Mechanical Approach for Blind Nasoenteric Tube Insertion

Overview

This study evaluates the feasibility and outcomes of a pharmaco-mechanical protocol for blind nasoenteric tube insertion in frail elderly patients with chronic wounds.

Background

As the population ages, frailty syndrome and chronic wounds are increasingly prevalent in older adults, significantly impacting their health and quality of life. Malnutrition is both a cause and consequence of frailty, necessitating effective nutritional interventions. The complexity of nasoenteric tube insertion poses challenges, particularly in frail patients.

Data Highlights

MeasurePre-InsertionPost-Insertion
Success Rate-76.2%
Insertion Time (min)-40 ± 9.2
Insertion Depth (cm)-101 ± 11.0
Serum Total Protein-Improved (p < 0.05)
Albumin Levels-Improved (p < 0.05)
Prealbumin Levels-Trend toward improvement (p = 0.05)
Infection Markers-No significant change (p > 0.05)

Key Findings

  • The overall procedural success rate for blind NET insertion was 76.2%.
  • Mean total insertion time was 40 ± 9.2 minutes.
  • Significant improvements in serum total protein and albumin levels were observed post-insertion.
  • No insertion-related complications were reported, indicating a favorable safety profile.
  • Learning curve analysis showed rapid skill acquisition among nursing staff.

Clinical Implications

The study suggests that the pharmaco-mechanical synergy protocol for blind NET insertion is a viable option for improving nutritional status in frail older adults with chronic wounds. The favorable safety profile and high success rates indicate its potential for broader clinical application.

Conclusion

The findings support the use of a pharmaco-mechanical approach for blind nasoenteric tube insertion in frail elderly patients, demonstrating significant improvements in nutritional markers and a favorable safety profile.

Related Resources & Content

  1. British Geriatrics Society, CGA: Nutrition and hydration, 2025 -- Nutrition and hydration
  2. StatPearls, Nasogastric Tube Insertion, 2026 -- Nasogastric Tube Insertion
  3. Intensive Care Medicine, 2018 -- Comparison of Erythromycin and Metoclopramide for Facilitating Post-Pyloric Spiral Nasoenteric Tube Insertion
  4. Obesity Surgery — Management of Chronic Large Gastrocutaneous Fistulas Following Bariatric Surgery: Initial Insights from Endoscopic Kehr’s T-Tube Insertion
  5. Comparison of Mucosal Advancement Flap and Inter-Sphincteric Fistula Tract Ligation for Treating Trans-Sphincteric Perianal Fistulas in Older Adults: A Retrospective Analysis
  6. BJS (British Journal of Surgery) — Optimizing Perioperative Management for Surgical Patients in the Elderly Population
  7. CGA: Nutrition and hydration | British Geriatrics Society
  8. Nasogastric Tube Insertion - StatPearls - NCBI Bookshelf
  9. Erythromycin plus metoclopramide combination therapy compared with erythromycin or metoclopramide monotherapy for postpyloric spiral nasoenteric tube placement: a multicenter, open-label, randomized controlled superiority trial - ScienceDirect

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