Retraction Note: Lycorine inhibits angiogenesis by docking to PDGFRα - Report - MDSpire
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Withdrawal Notice: Lycorine's Role in Angiogenesis Inhibition via PDGFRα Interaction

  • By

  • Fei Lv

  • XiaoQi Li

  • Ying Wang

  • September 11, 2026

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Clinical Report: Withdrawal Notice on Lycorine's Role in Angiogenesis Inhibition

Overview

The article discussing lycorine's role in angiogenesis inhibition has been retracted due to data integrity concerns. The editors lost confidence in the findings after observing apparent overlaps in experimental conditions.

Background

The integrity of published research is crucial for advancing clinical knowledge and practice. Retractions can significantly impact ongoing research, particularly in oncology.

Data Highlights

No numerical or trial data is available due to the retraction of the article.

Key Findings

  • The article was retracted due to concerns about data integrity.
  • Apparent overlaps were observed in experimental conditions presented in the article.
  • The authors did not address the concerns raised by the editors.
  • The editors no longer have confidence in the article’s data and conclusions.
  • No response was received from the authors regarding the retraction.

Clinical Implications

Healthcare professionals should be aware of the retraction of studies and critically evaluate the integrity of research data.

Conclusion

The article has been retracted due to concerns about data integrity.

Related Resources & Content

  1. BMC Cancer, 2022 -- Withdrawal Notice: Lycorine's Role in Angiogenesis Inhibition via PDGFRα Interaction
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  4. Journal of Gastroenterology — Combined Inhibition of FGFR and VEGFR Effectively Limits Hexokinase 2-Driven Lymphangiogenesis and Immune Evasion in Intrahepatic Cholangiocarcinoma
  5. Basic Research in Cardiology — Characterization and Advancement of Natural Anti-Fibrotic Compounds with Enhanced Efficacy
  6. Integrating multiple outcomes of first-line immunotherapy-based regimens for advanced hepatocellular carcinoma: A network meta-analysis of phase III trials - ScienceDirect
  7. Functional and clinical roles of stromal PDGF receptors in tumor biology | Cancer and Metastasis Reviews | Springer Nature Link
  8. Gastrointestinal Stromal Tumors Treatment (PDQ®) - NCI

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