Performance of AI in Predicting the Progression of Gestational Diabetes to Type 2 Diabetes: Systematic Review and Meta-Analysis - Report - MDSpire

Performance of AI in Predicting the Progression of Gestational Diabetes to Type 2 Diabetes: Systematic Review and Meta-Analysis

  • By

  • Alaa Abd-alrazaq

  • Shahira Padinharepattel Mohamed

  • Mohannad Alajlani

  • Aliya Tabassum

  • José Manuel Ordóñez-Mena

  • Shehel Yoosuf

  • Mais Alkhateeb

  • Arfan Ahmed

  • Mohammed Bashir

  • Junaid Qadir

  • Ali AlSanousi

  • Javaid Sheikh

  • July 9, 2026

  • 0 min

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Clinical Report: Efficacy of Artificial Intelligence in Forecasting GDM to T2DM

Overview

This systematic review and meta-analysis evaluate the effectiveness of artificial intelligence (AI) in predicting the transition from gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM).

Background

Gestational diabetes mellitus (GDM) significantly increases the risk of developing type 2 diabetes mellitus (T2DM) in women, with a reported progression rate of 30%-50% within 5 to 10 years postpartum. The rising prevalence of GDM necessitates effective screening and intervention strategies.

Data Highlights

No specific numerical data or trial results were provided in the source material.

Key Findings

  • Women with a history of GDM have a tenfold higher risk of developing T2DM compared to those with normoglycemic pregnancies.
  • 30%-50% of women with previous GDM develop T2DM within 5 to 10 years postpartum.
  • The annual rate of progression from GDM to T2DM is estimated at 9.6% based on a meta-analysis of 170,139 women.
  • Compliance with postpartum diabetes screening recommendations is low, reported at 16%-19%.
  • AI models have shown potential in identifying women at risk for T2DM following GDM.

Clinical Implications

Structured follow-up and screening for women with a history of GDM are important to prevent the onset of T2DM.

Conclusion

The use of AI in predicting the transition from GDM to T2DM is being explored for its potential in postpartum care.

Related Resources & Content

  1. Vounzoulaki E, Khunti K, Abner SC, et al., BMJ, 2020 -- Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis
  2. Ferrara A, Diabetes Care, 2007 -- Increasing prevalence of gestational diabetes mellitus: a public health perspective
  3. Li Z, Cheng Y, Wang D, et al., J Diabetes Res, 2020 -- Incidence rate of type 2 diabetes mellitus after gestational diabetes mellitus: a systematic review and meta-analysis of 170,139 women
  4. Shah BR, Lipscombe LL, Feig DS, et al., BJOG, 2011 -- Missed opportunities for type 2 diabetes testing following gestational diabetes: a population-based cohort study
  5. Frontiers in Endocrinology — Prediction models for progression from prediabetes to diabetes: a systematic review and meta-analysis
  6. Frontiers in Digital Health — Artificial intelligence for predicting and preventing adverse pregnancy outcomes addressing bias and clinical translation
  7. The Journal of Clinical Endocrinology & Metabolism — Artificial Intelligence Model for Predicting Large-for-Gestational-Age Infants in Pregnant Women with Gestational Diabetes Mellitus
  8. conexiant — Can AI Predict Preterm Birth in Diabetic, Hypertensive Pregnancies?
  9. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2026
  10. Global evidence on risk factors for the progression of gestational diabetes to type 2 diabetes
  11. Traditional statistics and artificial intelligence-based prognostic models for predicting type 2 diabetes mellitus after gestational diabetes: a systematic review | Diagnostic and Prognostic Research | Springer Nature Link

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