Association of Reduced Pillow Height with LPR in GERD Patients: A Retrospective Study at a Single Center - Report - MDSpire

Association of Reduced Pillow Height with LPR in GERD Patients: A Retrospective Study at a Single Center

  • By

  • Huiru Cao

  • Hui Yin

  • Linzhen Li

  • Shaofeng Liu

  • Xiaoping Niu

  • October 31, 2025

  • 0 min

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Clinical Report: Association of Reduced Pillow Height with LPR in GERD Patients

Overview

This study investigates the association between reduced pillow height and laryngopharyngeal reflux (LPR) in patients with gastroesophageal reflux disease (GERD). Findings suggest that lower pillow height may be a contributing factor to the development of LPR in GERD patients, highlighting the need for lifestyle modifications in this population.

Background

Gastroesophageal reflux disease (GERD) is a prevalent condition that significantly impacts patients' quality of life. Laryngopharyngeal reflux (LPR) is a common complication of GERD, associated with severe symptoms and increased healthcare utilization. Understanding the risk factors for LPR in GERD patients is crucial for effective management and prevention strategies.

Data Highlights

ParameterGERD without LPRGERD with LPR
Pillow HeightHigherLower
Symptom SeverityLess SevereMore Severe

Key Findings

  • Patients with GERD and LPR exhibited lower pillow heights compared to those without LPR.
  • Lower pillow height was associated with increased severity of LPR symptoms.
  • GERD patients with a history of cervical spondylosis were more likely to have LPR.
  • Patients with LPR reported poorer health-related quality of life compared to those without LPR.
  • Long-term LPR can lead to serious complications, including chronic pharyngitis and potential laryngeal cancer.

Clinical Implications

Healthcare providers should consider advising GERD patients to maintain a lower pillow height to potentially reduce the risk of developing LPR. Additionally, addressing cervical spondylosis in these patients may further aid in symptom management and improve overall quality of life.

Conclusion

The findings of this study underscore the importance of lifestyle modifications, such as pillow height adjustment, in managing GERD and its complications. Further research is warranted to explore the mechanisms behind these associations.

References

  1. BMC Gastroenterology, 2025 -- Low pillow height is associated with LPR among patients with GERD: a retrospective single-center study
  2. Journal of Gastroenterology, 2025 -- Links Between Increased Supragastric Belching and Esophageal Reflux Factors in Japanese Patients with PPI-Resistant GERD
  3. Drugs - Real World Outcomes, 2025 -- Evaluation of the Impact of Partial Response to Standard Proton Pump Inhibitor Doses in Patients with Clinically Confirmed Gastroesophageal Reflux Disease: Insights from a Real-World Study in India
  4. Surgical Endoscopy, 2025 -- Sustained Effectiveness and Impact on Quality of Life Following Antireflux Surgery
  5. The San Diego consensus for laryngopharyngeal symptoms and laryngopharyngeal reflux disease, 2025
  6. Sleep Positional Therapy for Nocturnal Gastroesophageal Reflux: A Double-Blind, Randomized, Sham-Controlled Trial - ScienceDirect
  7. Obesity Surgery — Criteria for Diagnosing Gastro-esophageal Reflux After Sleeve Gastrectomy
  8. The San Diego consensus for laryngopharyngeal symptoms and laryngopharyngeal reflux disease
  9. Sleep Positional Therapy for Nocturnal Gastroesophageal Reflux: A Double-Blind, Randomized, Sham-Controlled Trial - ScienceDirect
  10. Low pillow height is associated with LPR among patients with GERD: a retrospective single-center study | BMC Gastroenterology | Full Text

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