SARS-CoV-2 and reproductive system: a scientometric study - Report - MDSpire

SARS-CoV-2 and reproductive system: a scientometric study

  • By

  • Linghan Zhang

  • Minkai Wang

  • Huijuan Zhang

  • Genhong Mao

  • May 14, 2026

  • 0 min

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Clinical Report: Investigating the Relationship Between SARS-CoV-2 and the Reproductive System

Overview

This report analyzes the scientific literature on the relationship between SARS-CoV-2 and the reproductive system, revealing a declining trend in research output and highlighting emerging topics such as etiology and sperm viability. The findings underscore the need for further investigation into the long-term effects of SARS-CoV-2 on reproductive health.

Background

The impact of SARS-CoV-2 on various organ systems, including the reproductive system, is an area of growing concern, particularly in light of long COVID and its potential implications for fertility. Understanding the mechanisms by which SARS-CoV-2 affects reproductive health is crucial for public health and clinical practice. This study employs scientometric analysis to map the current state of research in this field and identify key trends and gaps.

Data Highlights

YearPublications
2020-20252,354
Predicted publications by 2030Nearly zero

Key Findings

  • Annual publication output has declined since 2022.
  • China and the USA are the leading contributors to research in this area.
  • Etiology and sperm viability are emerging topics of interest since 2025.
  • The most cited document is related to the cytokine storm phenomenon.
  • Research collaborations are primarily among the USA, China, Italy, and Germany.

Clinical Implications

Healthcare professionals should be aware of the potential long-term effects of SARS-CoV-2 on reproductive health, particularly in male fertility. Continued research and monitoring of this area are essential for informing clinical practices and public health strategies.

Conclusion

This report highlights significant trends and gaps in the research on SARS-CoV-2's impact on the reproductive system, emphasizing the need for ongoing investigation to better understand and address public health concerns.

Related Resources & Content

  1. The Journal of Infectious Diseases, 2024 -- Disparate SARS-CoV-2 Infection Outcomes Abound, but What Makes SARS-CoV-2 Bound for Rebound?
  2. JAMA Network Open, 2024 -- SARS-CoV-2 Infection and Rates of Neonatal Congenital Anomalies
  3. Basic Research in Cardiology, 2021 -- Investigating Cardiac Changes Associated with COVID-19 Infection
  4. JAMA Network Open, 2024 -- SARS-CoV-2 in Pregnancy—More Hints of Rare Complications
  5. ACOG, 2025 -- ACOG Releases Updated Maternal Immunization Guidance for COVID-19, Influenza, and RSV
  6. BMJ Public Health, 2025 -- Infection with SARS-CoV-2 during pregnancy and risk of stillbirth: a Scandinavian registry study
  7. J-GLOBAL, 2025 -- Association Between SARS-COV-2 Infection and Sperm DNA Fragmentation: A Systematic Review and Meta-Analysis
  8. ACOG Releases Updated Maternal Immunization Guidance for COVID-19, Influenza, and RSV | ACOG
  9. Infection with SARS-CoV-2 during pregnancy and risk of stillbirth: a Scandinavian registry study | BMJ Public Health
  10. Association Between SARS-COV-2 Infection and Sperm DNA Fragmentation: A Systematic Review and Meta-Analysis | Article Information | J-GLOBAL

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