Correction: Crosstalk between abnormal TSHR signaling activation and PTEN/PI3K in the dedifferentiation of thyroid cancer cells - Report - MDSpire

Correction: Crosstalk between abnormal TSHR signaling activation and PTEN/PI3K in the dedifferentiation of thyroid cancer cells

  • By

  • Fang Feng

  • Huiqin Han

  • Shuqi Wu

  • Hui Wang

  • July 17, 2026

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Clinical Report: Erratum on TSHR Signaling and PTEN/PI3K in Thyroid Cancer

Background

Dysregulated signaling pathways, such as TSHR and PTEN/PI3K, play significant roles in the progression and dedifferentiation of thyroid cancer cells.

Data Highlights

The original version of this article has been updated to correct an oversight in Figure 1.

Key Findings

  • The correction pertains to an image of TPC-1 in Figure 1B.
  • TSHR signaling and PTEN/PI3K pathways are implicated in thyroid cancer cell dedifferentiation.
  • Previous studies have linked abnormal signaling pathways to cancer progression.

Clinical Implications

Clinicians should be aware of the importance of accurate data representation in research publications. Understanding the role of TSHR and PTEN/PI3K pathways may inform future therapeutic strategies for thyroid cancer.

Conclusion

This erratum highlights the necessity for precision in scientific communication, particularly in the context of cancer research.

Related Resources & Content

  1. Feng F, Han H, Wu S, Wang H, Front. Oncol, 2021 -- Erratum: Interaction between Dysregulated TSHR Signaling and PTEN/PI3K Pathways in the Dedifferentiation of Thyroid Cancer Cells
  2. The Journal of Clinical Endocrinology & Metabolism — Linking Thyroid Differentiation Score to Survival Rates in Patients with Papillary Thyroid Carcinoma
  3. Brain — Erratum: Blocking YAP/TAZ-mediated TEAD function inhibits the proliferation of NF2-deficient schwannoma and meningioma
  4. The Journal of Clinical Endocrinology & Metabolism — Elevated NR1D1 Expression Indicates Potential Recurrence in Thyroid Carcinoma
  5. The Journal of Clinical Endocrinology & Metabolism — Activation of Wnt/β-Catenin Pathway and TP53 Mutations Correlate with Unique Immune Profiles in Advanced Thyroid Carcinomas
  6. 2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer - Matthew D. Ringel, Julie Ann Sosa, Zubair Baloch, Lindsay Bischoff, Gary Bloom, Gregory A. Brent, Pamela L. Brock, Roger Chou, Robert R. Flavell, Whitney Goldner, Elizabeth G. Grubbs, Megan Haymart, Steven M. Larson, Angela M. Leung, Joseph R. Osborne, John A. Ridge, Bruce Robinson, David L. Steward, Ralph P. Tufano, Lori J. Wirth, 2025

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