Clinical Report: Adherence to Treatment in Chronic Uveitis: Insights from the MARS-5 Assessment

Overview

This study evaluates medication adherence in chronic uveitis patients using the MARS-5 scale. It identifies barriers to adherence, highlighting the importance of addressing these challenges to improve treatment outcomes.

Background

Chronic uveitis is a significant cause of vision loss, particularly in young and middle-aged adults, necessitating long-term treatment. Effective management relies on patient adherence to prescribed therapies, which can be hindered by various factors. Understanding adherence patterns is crucial for optimizing clinical care and enhancing patient education.

Data Highlights

No numerical data was provided in the source material.

Key Findings

• Medication adherence was assessed using the MARS-5 scale among 114 patients with chronic uveitis.
• Barriers to adherence were identified through a questionnaire for patients scoring below the maximum on the MARS-5.
• Participants included adults aged 18 and older, with a focus on sociodemographic and disease-related factors.
• Previous studies have largely overlooked adherence in uveitis compared to other chronic ocular diseases.
• Effective management of uveitis requires addressing adherence to prevent complications and treatment failures.

Clinical Implications

Healthcare providers should prioritize assessing and addressing barriers to medication adherence in patients with chronic uveitis. Improved adherence can lead to better clinical outcomes and reduced healthcare costs associated with complications.

Conclusion

Enhancing medication adherence in chronic uveitis patients is essential for effective disease management. Further research is needed to explore specific barriers and develop targeted interventions.

References

1. Retinal Physician, 2023 -- UVEITIS CORNER: Medication Adherence and Patient Education in Management of Chronic Uveitis
2. Ophthalmology Management, 2010 -- Getting Uveitis Under Control –Quickly
3. Ophthalmology Management, 2018 -- Systemic therapy for non-infectious uveitis
4. Uveitis in Adults : JAMA, 2025 -- Uveitis in Adults: A Review
5. Clinical Rheumatology — Rheumatologists’ Compliance with Disease Activity Score-Guided Treatment Protocols in Early Arthritis Patients Decreases When the Goal is Remission
6. Uveitis in Adults : JAMA
7. Adalimumab versus Conventional Immunosuppression for Uveitis (ADVISE) Trial - ScienceDirect
8. Treatment adherence in chronic uveitis: What does the MARS-5 tell us? - PMC