Maternal and Peri/Neonatal Mortality and Morbidity in Midwife-Assisted Low-Risk Birth Outside Hospital Compared to Obstetric Team-Assisted Low-Risk Hospital Birth: A Systematic Review and Meta-Analysis - Report - MDSpire

Comparative Analysis of Maternal and Perinatal Mortality and Morbidity in Low-Risk Births Assisted by Midwives Outside of Hospitals Versus Those Managed by Obstetric Teams in Hospital Settings: A Systematic Review and Meta-Analysis

  • By

  • Carolina Herding

  • Ulla-Britt Wennerholm

  • Anders Elfvin

  • Sara Holm

  • Karolina Linden

  • Jahangir Khan

  • Max Petzold

  • Christina Bergh

  • Petteri Sjögren

  • Ida Stadig

  • Ann Liljegren

  • Ylva Carlsson

  • Verena Sengpiel

  • July 20, 2026

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Clinical Report: Maternal and Perinatal Outcomes in Low-Risk Births

Overview

This systematic review and meta-analysis compares maternal and perinatal mortality and morbidity between planned midwife-assisted home or freestanding midwifery unit births and obstetric team-assisted hospital births in low-risk populations.

Background

The choice of birth setting is significant for women with low-risk pregnancies. Understanding the risks and benefits of different birth settings is crucial for informed decision-making.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • Out-of-hospital births may offer higher maternal satisfaction and fewer obstetric interventions.
  • Conflicting evidence exists regarding neonatal outcomes, particularly higher mortality rates reported in some studies for planned out-of-hospital births.
  • International variations in out-of-hospital birth rates reflect differences in healthcare systems.
  • Previous reviews lacked applicability to strictly defined low-risk populations.
  • There is a need for rigorous evidence synthesis to clarify risks and benefits.

Clinical Implications

Healthcare providers should communicate regarding the safety and outcomes associated with different birth settings.

Conclusion

This systematic review highlights the need for further investigation into the safety of planned out-of-hospital births compared to hospital births for low-risk populations.

Related Resources & Content

  1. Authors, Source, Year -- Comparative Analysis of Maternal and Perinatal Mortality and Morbidity
  2. DIGITAL HEALTH — The use of digital solutions for the reduction of maternal and perinatal mortality: A systematic review
  3. American Journal of Epidemiology — Examining Racial and Ethnic Disparities in Severe Maternal and Neonatal Morbidity Among Low-Risk Nulliparous Patients: The Role of Labor and Delivery Unit Practices
  4. Frontiers in Medicine — Maternal age 30–34 years and adverse perinatal outcomes: a systematic review and meta-analysis
  5. conexiant — WHO Checklist Linked to Lower Stillbirths
  6. NICE Intrapartum Care Guidance
  7. Providing Care for Infants Born at Home
  8. Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study - PMC
  9. https://mellanarkiv-offentlig.vgregion.se/alfresco/s/archive/stream/public/v1/source/available/sofia/su4372-2081313122-161/native/2025_145%20Planned%20home%20birth%202025-11-21.pdf
  10. Perinatal or neonatal mortality among women who intend at the onset of labour to give birth at home compared to women of low obstetrical risk who intend to give birth in hospital: A systematic review and meta-analyses - PMC

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