HPV vaccine hesitancy among Chinese adults and its influencing factors in the context of improved vaccine accessibility - Report - MDSpire

HPV vaccine hesitancy among Chinese adults and its influencing factors in the context of improved vaccine accessibility

  • By

  • Yanqiu Chen

  • Shiqi Xie

  • Jianrong Zhou

  • Hongjin Zhu

  • May 25, 2026

  • 0 min

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Factors Influencing HPV Vaccine Hesitancy Among Adults in China

Overview

This study identifies key factors influencing HPV vaccine hesitancy among adults in China, revealing a 19.86% hesitancy rate. Significant predictors include higher complacency, lower confidence, and lower HPV knowledge.

Background

HPV vaccination is essential for preventing HPV-related diseases, yet hesitancy poses a significant barrier to achieving adequate vaccination coverage. In China, despite improved vaccine availability and policies, low vaccination rates indicate the need to understand the determinants of vaccine hesitancy among adults.

Data Highlights

DemographicHPV Vaccine Hesitancy Rate
Overall19.86%
Men26.5%
Women18.6%

Key Findings

  • The mean age of participants was 33.41 years, with 84.4% being women.
  • HPV vaccine hesitancy was found to be 19.86% overall.
  • Men exhibited a higher hesitancy rate (26.5%) compared to women (18.6%).
  • Higher complacency, lower confidence, and lower HPV knowledge were significant predictors of vaccine hesitancy.
  • Future interventions should focus on improving HPV knowledge, especially among men and older women.

Clinical Implications

Healthcare providers should prioritize educational initiatives to enhance HPV knowledge and address complacency among adults. Tailored interventions may be necessary to rebuild confidence in the HPV vaccine, particularly in demographics exhibiting higher hesitancy.

Conclusion

Addressing HPV vaccine hesitancy is critical for improving vaccination rates in China. Targeted strategies that enhance knowledge and confidence can help mitigate the factors contributing to hesitancy.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. American Journal of Epidemiology, 2022 -- Attributable Impact of Vaccine Hesitancy on Nonvaccination and Undervaccination Rates for COVID-19 in 2022
  3. Journal of Medical Internet Research (JMIR), 2026 -- Human Papillomavirus Vaccine Discourse and Sentiment on Reddit Before and After COVID-19
  4. WHO, 2025 -- China takes historic step to protect women’s health: HPV vaccine joins national immunization programme
  5. Effectiveness, immunogenicity, and safety of the quadrivalent HPV vaccine in women and men aged 27–45 years - PMC
  6. Effect of vaccine hesitancy on female college students’ willingness to receive the HPV vaccine in China: a multicenter cross-sectional study | BMC Public Health
  7. The ASCO Post — Make Vaccination Great Again
  8. China takes historic step to protect women’s health: HPV vaccine joins national immunization programme
  9. Effectiveness, immunogenicity, and safety of the quadrivalent HPV vaccine in women and men aged 27–45 years - PMC
  10. Effect of vaccine hesitancy on female college students’ willingness to receive the HPV vaccine in China: a multicenter cross-sectional study | BMC Public Health | Full Text

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