Case report and literature review: the effect of surgical management in intrathoracic pseudomyxoma peritonei - Report - MDSpire

Case report and literature review: the effect of surgical management in intrathoracic pseudomyxoma peritonei

  • By

  • De-Wang Ren

  • Zhi-Yuan Wang

  • Li-Bin Miao

  • Wei-Qiang Lu

  • Run-Yang Ma

  • Xue-Jun Dou

  • May 18, 2026

  • 0 min

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Clinical Report: Surgical Intervention Outcomes in Intrathoracic Pseudomyxoma Peritonei

Overview

This report evaluates the surgical outcomes of six patients with intrathoracic pseudomyxoma peritonei (PMP). The findings indicate that while surgical intervention can alleviate symptoms, long-term survival remains limited, with a 3-year survival rate of 33.3%.

Background

Intrathoracic metastasis from pseudomyxoma peritonei is rare and associated with poor prognosis. There are no established treatment guidelines, making management challenging for healthcare providers. Understanding surgical outcomes in this context is crucial for improving patient care and outcomes.

Data Highlights

Outcome1-Year Survival Rate3-Year Survival Rate
Overall100% (6/6)33.3% (2/6)

Key Findings

  • Six patients with intrathoracic PMP underwent surgical intervention from 2013 to 2022.
  • Five patients showed direct invasion into the pleural space.
  • Four patients had parietal/visceral pleurectomy to remove mucinous tissue.
  • One patient received lobectomy due to pulmonary metastases.
  • All patients experienced macroscopic tumor resection.
  • Average follow-up duration was 24 months.

Clinical Implications

Surgical intervention may provide symptomatic relief for patients with intrathoracic PMP, but the potential for long-term survival is limited. Clinicians should remain vigilant for perioperative complications and consider the overall prognosis when discussing treatment options with patients.

Conclusion

Intrathoracic pseudomyxoma peritonei presents significant treatment challenges, and while surgical approaches can alleviate symptoms, they do not guarantee improved long-term survival.

Related Resources & Content

  1. BJS (British Journal of Surgery), 2023 -- Advancements in the Prevention and Management of Peritoneal Metastases Through Cytoreductive Surgery
  2. Surgical Endoscopy, 2022 -- Comprehensive Analysis of Intra-Thoracic Oesophageal Perforation Management in a Tertiary Care Setting: A 15-Year Review of Short- and Long-Term Outcomes and Evolving Practices
  3. Journal of Gastrointestinal Surgery, 2017 -- Cytoreductive Surgery and HIPEC: Insights from a Single-Center Study in Austria
  4. Consensus guideline for the management of patients with appendiceal tumors, part 2: Appendiceal tumors with peritoneal involvement - PubMed, 2023
  5. Initial Postoperative Outcomes Following Thymectomy for Thymic Neoplasms: Insights from a Single-Center Study
  6. The Role of Prognostic Clinical-Pathological, (Immuno-) Histological, and Molecular Parameters in Pseudomyxoma Peritonei Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Systematic Review and Meta-Analysis
  7. Case report and literature review: The effect of Surgical Management in Intrathoracic Pseudomyxoma peritonei
  8. Consensus guideline for the management of patients with appendiceal tumors, part 2: Appendiceal tumors with peritoneal involvement - PubMed

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