Evidence-based care pathways for people with dementia and neurodegenerative disorders in Europe: a systematic review of models, integration of digital technologies, and quality indicators - Report - MDSpire

Evidence-based care pathways for people with dementia and neurodegenerative disorders in Europe: a systematic review of models, integration of digital technologies, and quality indicators

  • By

  • Maria Isabel Cardona

  • Parthena Nena Gakoudis

  • Jūratė Macijauskienė

  • Jochen René Thyrian

  • June 29, 2026

  • 0 min

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Clinical Report: Systematic Review of Evidence-Based Care Models for Dementia

Overview

This systematic review synthesizes evidence on dementia and neurodegenerative care pathways in Europe, following PRISMA 2020 guidelines. It identifies common organizational functions and proposes a conceptual framework to enhance care delivery based on findings from 81 studies across 11 European countries.

Background

Dementia and neurodegenerative disorders significantly impact European health systems, leading to increased hospitalizations and care demands, as evidenced by various studies. Effective care pathways are essential for improving continuity of care and addressing the complex needs of patients and caregivers. The integration of digital technologies into these pathways presents opportunities for more personalized and efficient care.

Data Highlights

The review included 81 studies from 11 European countries, focusing on care pathways for dementia and neurodegenerative disorders, with a variety of methodologies and outcomes assessed.

Key Findings

  • Most studies emphasized early-stage processes such as referral, diagnosis, and initial support, with limited focus on later-stage elements like long-term management and palliative care.
  • A consistent functional core across studies included care coordination, multidisciplinary teamwork, and caregiver involvement.
  • Substantial heterogeneity in study designs limited comparability across contexts.
  • The review proposes an evidence-informed conceptual framework for dementia care pathways based on the synthesized findings.

Clinical Implications

Healthcare professionals should consider the identified core functions in developing care pathways for dementia, as these findings reflect patterns in the literature rather than direct clinical recommendations.

Conclusion

The review highlights the importance of structured care pathways in managing dementia and neurodegenerative disorders, advocating for a more integrated approach to care delivery based on the evidence synthesized.

Related Resources & Content

  1. Journal of Medical Internet Research (JMIR), 2026 -- Effectiveness of eHealth Interventions in Alleviating Burden on Informal Caregivers of People With Dementia
  2. Frontiers in Medicine, 2026 -- Editorial: Transforming dementia caregiving through assistive technologies
  3. Frontiers in Digital Health, 2026 -- A European framework for the assessment of digital health technologies: conceptual advances, challenges, and future directions
  4. DIGITAL HEALTH, 2026 -- Digital tools and biomarkers for cognitive screening: A systematic review
  5. Alzheimer’s Association, 2025 -- Clinical guideline on use of blood-based biomarkers for diagnosing Alzheimer’s disease in specialist settings
  6. Telemedicine shows promise in improving dementia care, WHO study finds
  7. EN E-000880/2025 Answer given by Mr Várhelyi on be
  8. Alzheimer’s Association issues clinical guideline on use of blood-based biomarkers for diagnosing Alzheimer’s disease in specialist settings | Alzheimer Europe

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