Clinical Report: Case Report and Narrative Review of a Large Solid Pseudopapillary Neoplasm in an Adolescent Female Patient

Background

Solid pseudopapillary neoplasm is a rare pancreatic tumor with low malignant potential, predominantly affecting adolescent girls and young women. Accurate preoperative assessment is crucial, especially for larger tumors that may complicate surgical interventions.

Data Highlights

No numerical or trial data available in the source material.

Key Findings

• The patient presented with acute abdominal pain after strenuous physical activity.
• Imaging revealed a giant mixed solid-cystic mass in the pancreatic body and tail.
• Histopathology confirmed solid pseudopapillary neoplasm with negative margins and no nodal metastasis.
• Immunohistochemistry supported the diagnosis with specific markers including beta-catenin and CD10.
• The surgical approach balanced oncologic safety and bleeding risk, resulting in an uneventful postoperative course.

Clinical Implications

Surgical strategy for giant solid pseudopapillary neoplasms should consider the risks of bleeding and the need for organ preservation.

Conclusion

This case illustrates the complexities of diagnosing and managing giant solid pseudopapillary neoplasms in adolescents.

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