Clinical Report: Cardiomyopathy Among Women with Acromegaly in Colombia
Overview
This study characterizes cardiomyopathy in women with acromegaly, revealing that nearly one-third of participants exhibited cardiomyopathy. Key factors associated with this condition include older age, hypertension, arrhythmias, and carpal tunnel syndrome, as identified in the study.
Background
Acromegalic heart disease (AHD) is a prevalent complication of acromegaly, leading to significant cardiovascular morbidity. Understanding the clinical features and contributing factors in women is crucial, as existing data in Latin America are limited. This study aims to analyze a multicenter registry focused on this population.
Data Highlights
Characteristic
Value
Total Women Included
116
Women with Cardiomyopathy
34 (29.3%)
Adjusted OR for Age
1.07 per year
Adjusted OR for Hypertension
3.9
Adjusted OR for Arrhythmias
2.8
Adjusted OR for Carpal Tunnel Syndrome
2.6
Key Findings
29.3% of women with acromegaly had cardiomyopathy.
Older age was significantly associated with cardiomyopathy (adjusted OR 1.07 per year).
Hypertension was present in 3.9 times more women with cardiomyopathy.
Arrhythmias were found to be 2.8 times more common in women with cardiomyopathy.
Carpal tunnel syndrome was 2.6 times more frequent in this group.
Clinical Implications
Clinicians should be vigilant for signs of cardiomyopathy and associated cardiovascular conditions in women with acromegaly, particularly those with older age and comorbidities.
Conclusion
The study reports a significant prevalence of cardiomyopathy among women with acromegaly, highlighting the importance of recognizing cardiovascular risks in this demographic.
by Santiago Sierra-Castillo, David Aristizabal-Colorado, Andres Arteaga-Arellano, Daniel Miranda-Brazales, Ysamar Aquino, Juan Andres Muñoz-Ordoñez, Daniel Sierra-Castillo, Juan C. Peláez Ortiz, David Alexander Vernaza Trujillo, Juan S. Izquierdo-Condoy, Clara Saldarriaga, Alin Abreu-Lomba
