Clinical Report: Relationship Between Neutrophil Percentage-to-Albumin Ratio and Chronic Subdural Hematoma
Overview
This study investigates the association between the neutrophil percentage-to-albumin ratio (NPAR) and chronic subdural hematoma (CSDH), revealing that NPAR is significantly higher in CSDH patients compared to healthy controls.
Background
Chronic subdural hematoma (CSDH) is a prevalent condition, particularly among the elderly, often resulting from minor trauma. The increasing incidence of CSDH poses significant clinical challenges, including severe symptoms and high recurrence rates.
Data Highlights
Parameter
CSDH Patients
Healthy Controls
P-Value
NPAR
15.31 ± 2.71
12.47 ± 1.97
< 0.001
Key Findings
NPAR was significantly higher in CSDH patients compared to healthy controls (P < 0.001).
Multivariate analysis indicated that NPAR is independently associated with CSDH (OR = 1.88, 95% CI: 1.41–2.51, P < 0.001).
NPAR demonstrated optimal discriminative efficacy with an AUC of 0.808.
Bootstrap validation yielded an optimism-corrected AUC of 0.907.
Age and sex stratification showed consistent results, with NPAR remaining significantly higher in CSDH across different age and sex groups.
Clinical Implications
Further validation in targeted screening populations is necessary before clinical implementation.
