Reactive lymphoid hyperplasia of the eustachian tube orifice presenting with aural fullness: a case report - Report - MDSpire

Reactive lymphoid hyperplasia of the eustachian tube orifice presenting with aural fullness: a case report

  • By

  • Lingping Ding

  • Qi Wu

  • Zhaoli Meng

  • June 25, 2026

  • 0 min

Share

Clinical Report: Aural Fullness Due to Reactive Lymphoid Hyperplasia

Overview

This case report details a 58-year-old male with persistent aural fullness and hearing loss caused by reactive lymphoid hyperplasia at the right eustachian tube orifice. The findings emphasize the importance of accurate diagnosis to avoid misdiagnosis of benign lesions as malignant.

Background

Reactive lymphoid hyperplasia (RLH) is a benign condition that can occur in rare anatomical sites such as the eustachian tube orifice. Most neoplastic lesions in this region are malignant, leading to potential misdiagnosis and overtreatment. Understanding RLH is crucial for clinicians to differentiate it from more serious conditions like nasopharyngeal carcinoma.

Data Highlights

Clinical FeatureDetails
Patient Age58 years
Symptoms Duration5 months
Mass Size1.0 cm × 1.4 cm
Histopathology ResultChronic mucosal inflammation with RLH

Key Findings

  • A 58-year-old male presented with aural fullness and hearing loss.
  • Initial diagnosis was otitis media with effusion, but symptoms persisted.
  • Nasal endoscopy revealed a neoplastic lesion at the right eustachian tube orifice.
  • Histopathological examination confirmed benign lymphoid hyperplasia without malignant cells.
  • Comprehensive evaluation and pathological confirmation are essential to avoid misdiagnosis.

Clinical Implications

Clinicians should consider reactive lymphoid hyperplasia in patients presenting with aural fullness and hearing loss, especially in the context of eustachian tube dysfunction. Accurate diagnosis through imaging and histopathology is vital to prevent unnecessary treatments.

Conclusion

This case highlights the importance of recognizing benign lesions like RLH at the eustachian tube orifice to avoid misdiagnosis and overtreatment. Comprehensive evaluation is essential for appropriate management.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Author(s)/Org, Source, Year -- Title
  3. Author(s)/Org, Source, Year -- Title
  4. Author(s)/Org, Source, Year -- Title
  5. NCCN Guidelines® Insights: Head and Neck Cancers, Version 2.2025 - PubMed
  6. NCCN Guidelines Insights
  7. https://pdfs.semanticscholar.org/6cda/3463d9059cc67aa7f492235165caaf9ccedb.pdf
  8. https://assets.cureus.com/uploads/case_report/pdf/295692/20241228-1202774-51cxoh.pdf
  9. Balloon dilatation of the Eustachian tube for obstructive Eustachian tube dysfunction in adults - PMC

Original Source(s)

Related Content