Neurophysiological mechanisms of breathing-based well-being practices: a narrative review for clinical application - Report - MDSpire

Neurophysiological mechanisms of breathing-based well-being practices: a narrative review for clinical application

  • By

  • Pravesh Sharma

  • Vaishnavi Veerareddy

  • Isu Hong

  • Marin Nycklemoe

  • Mahathi Kandimalla

  • Vamika Sharma

  • Tiffany L. Kung

  • Rowa Osman

  • Seokbeen Lim

  • Karunya K. Kandimalla

  • Maria I. Lapid

  • Paul H. Min

  • July 8, 2026

  • 0 min

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Clinical Report: Physiological Mechanisms Behind Breathing Techniques for Enhanced Well-Being

Overview

This narrative review explores how breathing techniques influence physiological processes, emphasizing their clinical applicability. It highlights the modulation of heart rate, blood pressure, and brain activity through controlled breathing practices.

Background

Breathing techniques have gained attention as non-pharmacological interventions for various health issues, including stress and cardiovascular regulation. Understanding the physiological mechanisms behind these practices is crucial for their effective application in clinical settings. Certain populations may require tailored approaches due to varying tolerability and potential risks associated with specific breathing techniques.

Data Highlights

No numerical or trial data provided in the article.

Key Findings

  • Breathing practices can engage vagal pathways, lowering heart rate and blood pressure.
  • Controlled breathing reduces activity in stress-related brain regions while enhancing networks for calm attention.
  • Changes in breathing depth influence cerebrospinal fluid movement, though evidence of waste clearance in humans is lacking.
  • Populations requiring caution include those with panic symptoms, significant cardiopulmonary disease, or pregnancy.

Clinical Implications

Clinicians should consider the physiological effects of breathing techniques when integrating them into patient care. Tailoring breathing practices to individual patient needs is essential, especially for those with specific health concerns.

Conclusion

Breathing techniques represent a potential area for enhancing well-being, with specific physiological mechanisms that warrant further investigation in clinical practice.

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