Clinical Report: Participant Preferences for Centralized Versus Remote Engagement
Overview
This secondary analysis of the EAS trial reveals that 40% of participants preferred centralized engagement, while 49.9% opted for remote participation. Significant differences were noted in preferences based on age and distance from the trial site.
Background
Understanding participant preferences in clinical trials is crucial for enhancing recruitment and retention strategies. Remote trials offer potential benefits such as increased accessibility but may also introduce barriers for certain populations. This study addresses the gap in empirical evidence regarding participant preferences for centralized versus remote engagement in clinical trials.
Data Highlights
Engagement Type
Percentage
Centralized
40.0%
Remote
49.9%
Mixed
10.1%
Key Findings
40.0% of participants chose centralized engagement, 49.9% remote, and 10.1% mixed.
Young adults were more likely to select centralized engagement (57.3%) compared to adolescent-parent dyads (68.5% preferred remote).
Participants living within 10 miles of CCHMC were more likely to choose centralized (54.5%) or mixed (57.8%) modalities.
Remote visits were predominantly selected by participants recruited through decentralized strategies (60.2%).
In-person biospecimen provision was overwhelmingly chosen by those selecting centralized visits (97.8%).
Clinical Implications
The findings suggest that age and geographical proximity significantly influence participant preferences for engagement in clinical trials. Tailoring recruitment strategies to accommodate these preferences may enhance participation rates and improve the overall effectiveness of clinical trials.
Conclusion
This analysis underscores the importance of understanding participant preferences in clinical trial design, particularly as remote engagement becomes more prevalent. Future trials should consider these factors to optimize participant recruitment and retention.
