Management of arterial hypotension in critically Ill children: a narrative review and practical approach - Report - MDSpire

Management of arterial hypotension in critically Ill children: a narrative review and practical approach

  • By

  • Hendryk Schneider

  • June 1, 2026

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Clinical Report: Approaches to Addressing Arterial Hypotension in Critically Ill Pediatric Patients

Overview

This review synthesizes evidence on the assessment and management of arterial hypotension in critically ill children, emphasizing the importance of mean arterial pressure (MAP) as a key parameter. It provides practical guidelines for clinicians to enhance the management of hypotension and improve patient outcomes.

Background

Arterial hypotension is a common and critical finding in pediatric intensive care, often indicating severe underlying conditions such as shock. The lack of universally accepted definitions and management strategies complicates the treatment of hypotension, which is associated with increased mortality and morbidity. Understanding and addressing hypotension effectively is essential for improving outcomes in critically ill children.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

  • Arterial hypotension is a late sign of decompensated shock and is linked to higher mortality and adverse outcomes.
  • Mean arterial pressure (MAP) is the preferred parameter for assessing hemodynamic status in critically ill children.
  • A pragmatic MAP target of at least the 10th percentile for age is recommended to balance risks of hypoperfusion and overtreatment.
  • Early assessment using multimodal parameters, including point-of-care echocardiography, is crucial for effective management.
  • Norepinephrine is supported as a first-line agent in cases of distributive shock.
  • Initial management should focus on identifying shock etiology and judicious fluid resuscitation with balanced crystalloids.

Clinical Implications

Clinicians should prioritize early recognition and management of arterial hypotension in critically ill pediatric patients to prevent progression to severe shock. Utilizing MAP as a guiding parameter and employing multimodal assessment techniques can enhance treatment strategies and improve patient outcomes.

Conclusion

This review offers a structured framework for the assessment and management of arterial hypotension in critically ill children, emphasizing the need for a comprehensive approach to improve clinical outcomes.

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  4. Epinephrine vs Norepinephrine as Initial Treatment in Children With Septic Shock | Pediatrics | JAMA Network
  5. Intensive Care Medicine — Annual Overview of Intensive Care Medicine, 2008: III. Pediatric Care, Ethical Considerations, Outcome Research, Critical Care Management, Sedation Practices, Pharmacological Insights, and Additional Topics
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  7. Critical Care (Springer) — Approaches to Managing Vasoplegic Shock After Resuscitation: Objectives, Techniques, and Outcomes
  8. Intensive Care Medicine — Guidelines for Managing Sepsis in Low-Resource Environments
  9. Frontiers | Management of Arterial Hypotension in Critically Ill Children: A Narrative Review and Practical Approach
  10. Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 | SCCM
  11. Highlights of the 2025 American Heart Association's Guidelines for CPR and ECC
  12. Balanced crystalloid versus saline for resuscitation in pediatric septic shock: a systematic review and meta-analysis | BMC Pediatrics | Springer Nature Link
  13. Protocol for a Randomized Controlled Trial to Evaluate a Permissive Blood Pressure Target Versus Usual Care in Critically Ill Children with Hypotension (PRESSURE) - PMC
  14. Epinephrine vs Norepinephrine as Initial Treatment in Children With Septic Shock | Pediatrics | JAMA Network Open | JAMA Network

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