Glycemic control and association with diabetes-related distress, self-management behavior, financial toxicity, and cost-related non-adherence: a mixed-methods study - Report - MDSpire

Glycemic control and association with diabetes-related distress, self-management behavior, financial toxicity, and cost-related non-adherence: a mixed-methods study

  • By

  • Abdulfatai Olamilekan Babaita

  • Iyabo Yewande Ademuyiwa

  • Michiko Moriyama

  • June 5, 2026

  • 0 min

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Clinical Report: Glycemic Management and Its Relationship with Diabetes-Related Distress

Overview

This study investigates the interplay between glycemic control, diabetes-related distress, self-care practices, and financial strain among patients with type 2 diabetes in Nigeria. Findings indicate that poor self-management and diabetes-related distress are significant predictors of poor glycemic control, highlighting the need for integrated care approaches.

Background

Diabetes mellitus poses a significant public health challenge, particularly in Nigeria, which has the highest diabetes burden in sub-Saharan Africa. The increasing prevalence of diabetes necessitates a comprehensive understanding of the psychosocial and financial factors influencing glycemic control. Poor glycemic management can lead to severe complications, underscoring the importance of addressing both emotional and behavioral determinants in diabetes care.

Data Highlights

MeasureValue
Mean HbA1c7.04% (SD: 2.2)
HbA1c ≥7%43% (n=152)
Diabetes-related distress32%
Poor self-management56%
Financial toxicity54%
Cost-related non-adherence48.3%

Key Findings

  • 43% of participants had HbA1c levels ≥7%, indicating poor glycemic control.
  • 32% of participants reported diabetes-related distress.
  • 56% exhibited poor self-management practices.
  • Financial toxicity and cost-related non-adherence were prevalent but not significantly associated with glycemic control.
  • Younger age, multiple antidiabetic medications, and lack of access to an endocrinologist were linked to poor glycemic control.
  • Qualitative interviews revealed difficulties in adapting to lifestyle changes and medication non-adherence among those with poor glycemic control.

Clinical Implications

Healthcare providers should prioritize diabetes education that incorporates behavioral modification strategies and psychological support. Additionally, improving access to endocrinologists and addressing financial barriers are crucial for enhancing glycemic management in patients with diabetes.

Conclusion

The study underscores the critical role of self-management and emotional well-being in achieving glycemic control among diabetes patients. Integrated care approaches that address both psychological and financial factors are essential for improving outcomes.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. American Diabetes Association, Diabetes Care, 2026 -- Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes—2026
  3. The Journal of Clinical Endocrinology & Metabolism, 2023 -- The Interplay Between Mental Health and Diabetes Care Management
  4. Frontiers in Endocrinology, 2023 -- Impact of continuous glucose monitoring on patient-reported outcomes in adults with type 2 diabetes: a Systematic Review and meta-analysis
  5. BMC Psychiatry, 2023 -- The effect of mental health-based self-care model counseling on anxiety and depression in women with gestational diabetes: a randomized clinical trial
  6. The Journal of Clinical Endocrinology & Metabolism — Nutritional Approaches for Weight Control and Glycemic Regulation in Individuals with Type 1 Diabetes: A Comprehensive Meta-analysis of Intervention Studies
  7. Nigeria Diabetes Trends & Health Data | IDF Atlas
  8. The role of depression and diabetes distress in glycemic control: A meta-analysis
  9. 6. Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes—2026 | Diabetes Care | American Diabetes Association

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