A Five-Year Analysis of Reconstruction Results Following Mohs Surgery for Periocular Skin Cancers at a Tertiary Care Facility - Report - MDSpire

A Five-Year Analysis of Reconstruction Results Following Mohs Surgery for Periocular Skin Cancers at a Tertiary Care Facility

  • By

  • Amanda K. Hertel

  • Aaron Veenis

  • Rachel Chu

  • Nathaniel Cameron

  • Nikki Gill

  • Irfan Ansari

  • Maggie Malmberg

  • Emilee Wells

  • Geethanjalee Mudunkotuwa

  • Isuru Ratnayake

  • Jason A. Sokol

  • April 28, 2026

  • 0 min

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Clinical Report: Reconstruction Results Following Mohs Surgery for Periocular Skin Cancers

Overview

This study analyzes post-Mohs reconstruction outcomes for periocular skin cancers, highlighting the challenges and solutions in reconstructive surgery. Key findings include a high rate of full eyelid function and acceptable cosmetic appearance, with specific complications noted.

Background

Periocular skin cancers, particularly basal cell carcinoma, are prevalent and require careful management due to their location and potential impact on eyelid function and aesthetics. Mohs micrographic surgery is the preferred treatment method, necessitating effective reconstruction strategies to optimize patient outcomes. Understanding the outcomes of these reconstructive procedures is essential for improving surgical techniques and patient care.

Data Highlights

ParameterValue
Mean Age67.7 years
Common MalignancyBasal Cell Carcinoma (70.6%)
LocationLower Lid (56.7%)
Reconstruction TypeModified Hughes Tarsoconjunctival Flap (24.7%)
Post-operative ComplicationsHealing Issues (6.7%), Ectropion (6.2%)
Full Eyelid Function93.3%
Acceptable Cosmetic Appearance94.8%

Key Findings

  • The most common periocular malignancy was basal cell carcinoma (70.6%).
  • Lower lid was the most frequent location for malignancies (56.7%).
  • Modified Hughes tarsoconjunctival flap was the most utilized reconstruction method (24.7%).
  • Post-operative complications included healing issues (6.7%) and ectropion (6.2%).
  • 93.3% of patients achieved full eyelid function post-surgery.
  • Adjuvant chemotherapy was linked to decreased cure rates (p = 0.0010) and recurrence (p = 0.0174).

Clinical Implications

Surgeons should consider the specific characteristics of periocular malignancies, such as location and defect size, when planning reconstruction after Mohs surgery. Awareness of potential complications, particularly ectropion and healing issues, is crucial for postoperative management and patient counseling.

Conclusion

Highlight the importance of researching factors affecting reconstruction outcomes.

Related Resources & Content

  1. Three-Dimensional Printing Facilitated Cranio-Orbital Reconstruction Using Customized Polyetheretherketone Implants Following Benign Spheno-Orbital Tumor Resection, Springer, 2024 -- Link
  2. Innovative Approaches in Neuroplastic Cranial Reconstruction: Interdisciplinary Strategies for Managing Neurosurgical Wound Healing Issues, Springer, 2024 -- Link
  3. Expect Questions About Mohs Micrographic Surgery, ASCO Post, 2020 -- Link
  4. A comprehensive evaluation of flap reconstruction in periocular repair: outcomes, complications, and future directions, BMC Ophthalmology, 2025 -- Link
  5. Retinal Physician — A Shift in Strategy for Ocular Melanoma
  6. Current NCCN guidance on Mohs micrographic surgery, Oregon.gov
  7. A comprehensive evaluation of flap reconstruction in periocular repair: outcomes, complications, and future directions | BMC Ophthalmology | Springer Nature Link

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