Latent transition analysis of home-based fluid management during the vulnerable phase in patients with chronic heart failure: impact on symptom burden - Report - MDSpire
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Latent transition analysis of home-based fluid management during the vulnerable phase in patients with chronic heart failure: impact on symptom burden
Clinical Report: Analysis of Latent Transitions in Home Fluid Management
Overview
This study investigates the transitions in home fluid management among chronic heart failure (CHF) patients and their correlation with symptom burden. Findings indicate that a significant proportion of patients experience changes in their management levels, impacting their symptom severity.
Background
Chronic heart failure (CHF) is a prevalent condition with high morbidity and mortality rates, particularly among older adults. Effective management during the vulnerable post-discharge period is crucial to prevent readmissions and improve patient outcomes. Home fluid management plays a key role in controlling symptoms and maintaining stability in CHF patients.
Data Highlights
Group
Transition Rate
Odds Ratio (OR)
High to Medium
7.94%
2.702
High to Low
3.17%
6.482
Persistent Medium
26.59%
4.477
Persistent Low
9.91%
11.917
Key Findings
Three latent profiles of home fluid management were identified: high, medium, and low-level groups.
50.39% of patients remained in their original latent state after three months.
21.03% of patients experienced a deterioration in their management status.
Patients in lower management groups had significantly higher symptom burden scores compared to the persistent high-level group.
Multivariate logistic regression indicated increased risks of high symptom burden for all non-high-level groups.
Clinical Implications
Healthcare providers should focus on individualized fluid management strategies during the critical post-discharge period for CHF patients. Monitoring transitions in home fluid management can help identify patients at risk for increased symptom burden and guide interventions to improve their quality of life.
Conclusion
The study highlights the importance of effective home fluid management in chronic heart failure patients, particularly during the vulnerable post-discharge phase, to mitigate symptom burden and enhance patient outcomes.
Despite major advances in guideline-directed medical therapy (GDMT), worsening heart failure continues to drive significant morbidity, repeat hospitalizations and healthcare utilization worldwide.
