Evaluation of Phacogoniosynechialysis Combined with Viscocanalostomy and Ologen Implant in Treating Primary Angle-Closure Glaucoma: A Pilot Retrospective Cohort Analysis

By
Ahmed A. M. Gad
Bahaa-Eldin Hasan Abdulhalim
Amr Mahfouz Mohammed
April 13, 2026
0 min

Bmc Ophthalmology

Overview

This pilot retrospective cohort analysis evaluates the efficacy and safety of phacogoniosynechialysis combined with viscocanalostomy and Ologen implant in treating primary angle-closure glaucoma (PACG) with significant peripheral anterior synechiae. The study highlights the potential of this combined surgical approach in managing medically uncontrolled PACG.

Background

Primary angle-closure glaucoma (PACG) is a serious condition characterized by elevated intraocular pressure and glaucomatous optic neuropathy, often requiring surgical intervention when medical management fails. The presence of extensive peripheral anterior synechiae complicates treatment, necessitating effective surgical strategies to restore aqueous outflow and control intraocular pressure. Understanding and improving surgical options for PACG is crucial for preventing vision loss in affected patients.

Data Highlights

No numerical data was provided in the source material.

Key Findings

Phacogoniosynechialysis combined with viscocanalostomy and Ologen implant may effectively manage PACG with significant PAS.
The study included patients aged 50 and above with medically uncontrolled IOP and at least 270° of PAS.
All surgeries were performed under peribulbar or general anesthesia, ensuring patient safety and comfort.
The target IOP was set according to European Glaucoma Society Guidelines, aiming to prevent further glaucomatous damage.
Previous studies suggest that early surgical intervention can improve outcomes in PACG patients.

Clinical Implications

The findings suggest that combining phacogoniosynechialysis with viscocanalostomy and Ologen implant may provide a viable surgical option for patients with PACG who do not respond to medical therapy. Clinicians should consider this approach in cases of extensive PAS to improve intraocular pressure control and prevent glaucomatous damage.

Conclusion

This study supports the potential of a combined surgical approach in managing PACG, highlighting the need for further research to establish long-term outcomes and efficacy. Effective surgical strategies are essential for improving patient care in glaucoma management.